Not long after she finished her medical residency at Stanford University about a decade ago, Nadine Burke Harris got to work as a pediatrician in the Bayview-Hunters Point neighborhood of San Francisco. She founded and became CEO of a clinic there, focused on addressing health disparities in the community.
It was in talking with those children and their families, she says, that she first realized how many of her patients experiencing the worst health outcomes — those with the highest levels of chronic asthma, for example — were also living with significant adversity, such as growing up in a household where a parent was mentally ill, abusive or substance dependent.
Eventually, those conversations led her to the expanding research on adverse childhood experiences, or ACEs, and their profound, lifelong health effects. The term “ACEs” has been used since the 1990s to describe the abuse, neglect and other potentially traumatic experiences estimated to afflict more than 34 million U.S. children under 18.
Burke Harris has dedicated much of her career to spreading the word to fellow doctors and the public about ACEs and the dangers of this toxic stress to children. She champions a multidisciplinary approach to helping these kids and teens.
In an interview last year, after her book, The Deepest Well: Healing the Long-Term Effects of Childhood Adversity, was published, Burke Harris told NPR’s Cory Turner, “We all need to be part of the solution. If we each take … our little piece, it’s nuts how far we’ll be able to go, together as a society, in terms of solving this problem.”
California Gov. Gavin Newsom took Burke Harris up on her challenge, appointing her the first-ever surgeon general of California. Newsom cites the toxic stress of childhood trauma as among the root causes “of many of the most harmful and persistent health challenges facing Californians.”

