Other Republicans who have announced their intention to run include former San Diego Mayor Kevin Faulconer, former U.S. Rep. Doug Ose and businessman John Cox, who lost handily to Newsom in the 2018 governor's race.
If the recall qualifies, Newsom would be forced to fend off rivals in the midst of a pandemic that has cost the state millions of jobs, cored government budgets and upended life for nearly 40 million residents.
He's also been hit by the fallout from a multibillion-dollar fraud scandal at the state unemployment agency while weathering a public shaming for dining out with friends and lobbyists at an exclusive San Francisco Bay Area restaurant last fall, while simultaneously telling residents to stay home for safety.
However, recent polling has suggested Newsom will likely hold his seat, and the sour public mood could shift as a growing number of schools and businesses reopen across the state. California also is likely to be the recipient of billions of dollars of federal recovery funds, which Newsom will dispense and could use to his political advantage.
Jenner made headlines in recent years with her ties to former President Donald Trump, who remains broadly unpopular in California outside his GOP base. Trump lost the heavily Democratic state to Joe Biden in November by more than 5 million votes.
Jenner supported Trump in 2016 but later criticized his administration's reversal of a directive on transgender access to public school bathrooms. She also criticized Trump after he said transgender people would not be allowed to serve in the U.S. military.
In a statement, Newsom campaign spokesman Dan Newman said, "We always knew the ... recall would be a ludicrous circus full of Trump supporters."