Iyana Spruell had not seen her older cousin, Sterling Ulrich, for about a decade when they reconnected last summer.
After exchanging messages, the cousins learned they lived only blocks apart in San Francisco. Spruell lived in the Tenderloin, and Ulrich lived in the neighborhood, on Market Street. Lacking a home, Ulrich had found shelter at Hotel Whitcomb when it opened for unhoused people during the pandemic, under a statewide program called Project Roomkey.
Ulrich and Spruell soon met up, drinking wine and reminiscing about the fun they had growing up together in Merced. As a kid, Ulrich had idolized Marilyn Monroe’s style and dreamed of being famous in Hollywood, Spruell said.
Ulrich was loving, stylish and unique.
When the cousins were younger, Spruell recalled, “[Ulrich] would dress me up, fix my hair, and say I need to be more girly. Let my hair down and just be you.”

During a meetup last year, Spruell says, Ulrich talked briefly about using drugs to feel happy, before quickly changing the subject to how nice it felt to be together again.
The reunited cousins didn’t have long to bond.
Last November, Ulrich fatally overdosed on meth and fentanyl at Hotel Whitcomb.
“I couldn’t believe it,” Spruell said. When she found out, she called Ulrich’s sister, and “when we talked on the phone, she started crying, and I started screaming.”
Hotel staff on the front lines of the city’s fentanyl crisis
About 400 unhoused people stay at Hotel Whitcomb, and many deal with substance use disorders. That reality has meant staff who work at the hotel are fighting to keep guests alive.
Eldridge Cruse is a supervisor at Hotel Whitcomb; he works for Five Keys Schools and Programs, the nonprofit overseeing the hotel. Cruse says he’s seen more deaths up close in the last two years than in his entire life.
“It’s frightening, it’s upsetting, it’s disturbing, to see human life hang in the balance,” he said. “You don’t know if this person is going to make it, if they’re going to come back.”
At 27, Sterling Ulrich was one of the youngest people to die at Hotel Whitcomb in the last two years. At least 18 people fatally overdosed there from April 2020, when it opened, to April 2022, according to preliminary data from the San Francisco Medical Examiner’s Office. That’s a more than a quarter of all overdose deaths in hotels that were opened during the pandemic to house vulnerable San Franciscans.
By contrast, zero people have fatally overdosed in Alameda County’s Project Roomkey hotels, according to the Alameda County Health Care Services Agency.
The risks of using drugs alone
San Francisco Department of Public Health officials knew early in the pandemic that people likely would fatally overdose at the city-run Project Roomkey hotels, known as shelter-in-place hotels. People who use drugs are at greater risk of dying when no one is around to administer Narcan, the brand name for naloxone, a medication used to reverse overdoses.
“There was a great deal of worry. We didn’t see any surprising number of overdoses because we had an expectation that there would be a risk. A lot of steps were taken to mitigate that,” said Barry Zevin, medical director of street medicine and shelter health for the San Francisco Department of Public Health.
SFDPH, the DOPE Project, and the San Francisco AIDS Foundation partnered to provide Narcan inside the hotels as well as training on how to use it. Hotel staff also regularly conduct wellness checks to look in on guests who use substances.
Cruse said he tries to reassure staff who feel responsible when they try to reverse overdoses but don’t succeed.
“Someone came to me one time and said, ‘I didn’t do enough,'” he said. He told his colleague, “‘No, you’re not to take on that burden that you didn’t do enough. You did everything that you could.'”

Fentanyl, which is up to 50 times stronger than heroin, can kill rapidly.
“People want to believe that when you give people Narcan it’s a magic pill. It’s magical sometimes, but it all depends on when we catch it,” Cruse said.
Earlier this year, a team of researchers at UCSF found that overdose mortality rates in San Francisco during the first year of the pandemic were lower for residents of shelter-in-place hotels than for people who were unhoused and not staying at these hotels.
But for staff who work at these sites, overdoses are traumatic, whether they’re fatal and not.
Grief and trauma for staff battling the city’s overdose crisis
Earlier this year, Meg O’Neil left her job as the director of housing services at Five Keys. She says one reason was the emotional toll of the job. She estimated that, since Hotel Whitcomb opened in April 2020, staff have used Narcan at least 1,000 times to respond to drug overdoses. O’Neil added that the numbers are hard to track. Because fentanyl is so powerful, staff often need to use more than one dose of Narcan to reverse overdoses.
“I just need space to do some healing around that,” she said. “It’s really scary to basically be an EMT but with people you know really well.”
O’Neil said staff also are dealing with many of the same challenges as the people they serve, such as substance use disorder and homelessness.
“[Staff] are coming out of incarceration, coming out of substance use or are newly in recovery,” she said. “We have staff members who are unhoused and we have people who can’t find a safe place to stay.”
Some of the staff commute from as far away as Modesto or Sacramento, unable to afford to live in the cities where they work.
Besieged in their own lives and on the job, staff, too, have relapsed, and some have fatally overdosed.


