Michael Pollan Embraces The 'New Science' Of Psychedelics
VIDEO: For LSD, What A Long Strange Trip It's Been
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the active ingredient in \"magic mushrooms\" — to help them deal with their distress.\u003c/p>\n\u003cp>\"This seemed like such a crazy idea that I began looking into it,\" Pollan says. \"Why should a drug from a mushroom help people deal with their mortality?\"\u003c/p>\n\u003cp>Pollan, whose previous books include \u003ca href=\"https://www.npr.org/books/titles/137946336/the-omnivores-dilemma-a-natural-history-of-four-meals\" target=\"_blank\" rel=\"noopener\">The Omnivore's Dilemma\u003c/a> and \u003ca href=\"https://www.npr.org/templates/story/story.php?storyId=17725932\" target=\"_blank\" rel=\"noopener\">In Defense Of Food\u003c/a>, started researching different experimental therapeutic uses of psychedelics, and found that the drugs were being used to treat depression, addiction and the fear of death.\u003c/p>\n\u003cp>Then he decided to go one step further: A self-described \"reluctant psychonaut,\" Pollan enlisted guides to help him experiment with LSD, psilocybin and 5-MeO-DMT, a substance in the venom of the Sonoran Desert toad.\u003c/p>\n\u003cp>Each of Pollan's experiences with psychedelics was preceded by worry and self-doubt. But, he says, \"I realized later that was my ego trying to convince me not to do this thing that was going to challenge my ego.\"\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Pollan's new book, \u003cem>How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence\u003c/em>, recounts his experiences with the drugs and also examines the history of psychedelics as well as their possible therapeutic uses.\u003c/p>\n\u003chr>\n\u003cp>\u003cstrong>Interview Highlights\u003c/strong>\u003c/p>\n\u003cp>\u003cstrong>On how the psychedelic psilocybin is administered in therapy for depression \u003c/strong>\u003c/p>\n\u003cp>The way [psilocybin is] being used is in a very controlled or guided setting. ... They don't just give you a pill and send you home; you're in a room. You're with two guides, one male, one female. You're lying down on a comfortable couch. You're wearing headphones listening to a really carefully curated playlist of music — instrumental compositions for the most part — and you're wearing eyeshades, all of which is to encourage a very inward journey.\u003c/p>\n\u003cp>Someone is kind of looking out for you, and they prepare you very carefully in advance. They give you a set of \"flight instructions,\" as they call them, which is what to do if you get really scared or you're beginning to have a bad trip. If you see a monster, for example, don't try to run away. Walk right up to it, plant your feet and say, \"What do you have to teach me? What are you doing in my mind?\" And if you do that, according to the flight instructions, your fear will morph into something much more positive very quickly.\u003c/p>\n\u003cp>\u003cstrong>On how psychedelics can help change the stories we tell about ourselves \u003c/strong>\u003c/p>\n\u003cp>The drugs foster new perspectives on old problems. One of the things our mind does is tell stories about ourselves. If you're depressed, you're being told a story perhaps that you're worthless, that no one could possibly love you, you're not worthy of love, that life will not get better. And these stories — which are enforced by our egos really — trap us in these ruminative loops that are very hard to get out of. They're very destructive patterns of thought.\u003c/p>\n\u003cp>What the drugs appear to do is disable for a period of time the part of the brain where the self talks to itself. It's called the \u003ca href=\"https://www.npr.org/tags/482443062/default-mode-network\" target=\"_blank\" rel=\"noopener\">default mode network\u003c/a>, and it's a group of structures that connect parts of the cortex — the evolutionarily most recent part of the brain — to deeper levels where emotion and memory reside. And it's a very important hub in the brain and lots of important things happen there: self-reflection and rumination, time travel. It's where we go to think about the future or the past, and theory of mind, the ability to imagine the mental states of other beings and, I think, most importantly, the autobiographical self. It's the part of the brain, it appears, where we incorporate things that happen to us, new information, with a sense of who we are, who we were and who we want to be. And that's where these stories get generated. And these stories can be really destructive, they trap us. ...\u003c/p>\n\u003cp>This network is downregulated [with psychedelics], it sort of goes offline for a period of time. And that's why you experience this dissolution of self or ego, which can be a terrifying or liberating thing, depending on your mindset. This is what allows people, I think, to have those new perspectives on themselves, to realize that they needn't be trapped in those stories and they might actually be able to write some new stories about themselves. That's what's liberating, I think, about the experience when it works.\u003c/p>\n\u003cp>\u003cstrong>On how psychedelics can help dying people face their deaths \u003c/strong>\u003c/p>\n\u003cp>\u003ca href=\"https://www.npr.org/tags/125941537/prozac\">Prozac\u003c/a> doesn't help when you're confronting your mortality. But here we have something that occasions an experience in people — a mystical experience — that somehow makes it easier to let go. And I think some of it has to do with the fact that you do experience the \"extinction\" of yourself and it's kind of a rehearsal for death. And I think that may be part of what helps people, that they expand their sense of what is your self-interest and your self-interest is something larger than what is contained by your skin. And when you have that recognition, I think dying becomes a little easier. ...\u003c/p>\n\u003cp>There's no way to prove this, obviously, and it's a question that really troubled me as an old-fashioned materialist skeptical journalist. It's like, \"What if these drugs are inducing an illusion in people?\" I got a variety of answers to that question from the researchers. One was, \"Who cares if it helps them?\" And I can see the point of that. The other was, \"Hey, this is beyond my pay grade; none of us know what happens after we die.\" And others say, \"Well, this is an open frontier.\" ...\u003c/p>\n\u003cp>The experiences that people have are very real to them — they're psychological facts. And one of the really interesting qualities of psychedelic experience is that the insights you have on them have a durability ... This isn't just an opinion, this is revealed truth, so the confidence people have is hard to shake, actually.\u003c/p>\n\u003cp>\u003cstrong>On a \u003c/strong>\u003ca href=\"https://www.hopkinsmedicine.org/news/stories/mushrooms_quit_smoking.html\" target=\"_blank\" rel=\"noopener\">\u003cstrong>Johns Hopkins study\u003c/strong>\u003c/a>\u003cstrong> on the use of psilocybin to help people quit smoking \u003c/strong>\u003c/p>\n\u003cp>Smoking is a very hard addiction to break. It's one of the hardest addictions to break. [I wanted to understand] how, after a single psilocybin trip, they could decide \"I'm never going to smoke again\" based on the perspective they had achieved. And they would say things like, \"Well, I had this amazing experience. I died three times. I sprouted wings. I flew through European histories. I beheld all these wonders. I saw my body on a funeral pyre on the Ganges. And I realized, the universe is so amazing and there's so much to do in it that killing myself seemed really stupid.\" And that was the insight. Yes, killing yourself is really stupid — but it had an authority it had never had. And that, I think, is the gift of these psychedelics.\u003c/p>\n\u003cp>\u003cstrong>On his own experience tripping on mushrooms \u003c/strong>\u003c/p>\n\u003cp>I had an experience that was by turns frightening and ecstatic and weird. ... I found myself in this place where I could no longer control my perceptions at all, and I felt my sense of self scatter to the wind — almost as if a pile of post-its had been released to the wind — but I was fine with it. I didn't feel any desire to pile the papers back together into my customary self ...\u003c/p>\n\u003cp>Then I looked out and saw myself spread over the landscape like a coat of paint or butter. I was outside myself, beside myself, literally, and the consciousness that beheld this ... was not my normal consciousness, it was completely unperturbed. It was dispassionate. It was content, as I watched myself dissolve over the landscape.\u003c/p>\n\u003cp>What I brought back from that experience was that I'm not identical to my ego, that there is another ground on which to plant our feet and that our ego is kind of this character that is chattering neurotically in our minds. And it's good for lots of things. I mean, the ego got the book written, but it also can be very harsh, and it's liberating to have some distance on it. And that was a great gift, I think.\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>\u003cem>Sam Briger and Seth Kelley produced and edited this interview for broadcast. Bridget Bentz, Molly Seavy-Nesper and Scott Hensley adapted it for the Web.\u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2018 Fresh Air. To see more, visit \u003ca href=\"http://www.npr.org/programs/fresh-air/\" target=\"_blank\" rel=\"noopener\">Fresh Air\u003c/a>.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=%27Reluctant+Psychonaut%27+Michael+Pollan+Embraces+The+%27New+Science%27+Of+Psychedelics+&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n","blocks":[],"excerpt":"Author Michael Pollan, who experimented with mushrooms, LSD and other psychedelics while researching his latest book, says: \"I had an experience that was by turns frightening and ecstatic and weird.\"","status":"publish","parent":0,"modified":1526688571,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":27,"wordCount":1487},"headData":{"title":"Michael Pollan Embraces The 'New Science' Of Psychedelics | KQED","description":"Author Michael Pollan, who experimented with mushrooms, LSD and other psychedelics while researching his latest book, says: "I had an experience that was by turns frightening and ecstatic and weird."","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Michael Pollan Embraces The 'New Science' Of Psychedelics","datePublished":"2018-05-19T01:00:02.000Z","dateModified":"2018-05-19T00:09:31.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"441705 https://ww2.kqed.org/futureofyou/?p=441705","disqusUrl":"https://ww2.kqed.org/futureofyou/2018/05/18/reluctant-psychonaut-michael-pollan-embraces-the-new-science-of-psychedelics/","disqusTitle":"Michael Pollan Embraces The 'New Science' Of Psychedelics","source":"Health","nprImageCredit":"Images Etc Ltd","nprByline":"Terry Gross, NPR","nprImageAgency":"Getty Images","nprStoryId":"611225541","nprApiLink":"http://api.npr.org/query?id=611225541&apiKey=MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004","nprHtmlLink":"https://www.npr.org/sections/health-shots/2018/05/15/611225541/reluctant-psychonaut-michael-pollan-embraces-the-new-science-of-psychedelics?ft=nprml&f=611225541","nprRetrievedStory":"1","nprPubDate":"Fri, 18 May 2018 16:43:00 -0400","nprStoryDate":"Tue, 15 May 2018 13:17:00 -0400","nprLastModifiedDate":"Fri, 18 May 2018 16:43:05 -0400","nprAudio":"https://ondemand.npr.org/anon.npr-mp3/npr/fa/2018/05/20180515_fa_01.mp3?orgId=427869011&topicId=1066&d=2549&p=13&story=611225541&ft=nprml&f=611225541","nprAudioM3u":"http://api.npr.org/m3u/1611333046-6f3747.m3u?orgId=427869011&topicId=1066&d=2549&p=13&story=611225541&ft=nprml&f=611225541","path":"/futureofyou/441705/reluctant-psychonaut-michael-pollan-embraces-the-new-science-of-psychedelics","audioUrl":"https://ondemand.npr.org/anon.npr-mp3/npr/fa/2018/05/20180515_fa_01.mp3?orgId=427869011&topicId=1066&d=2549&p=13&story=611225541&ft=nprml&f=611225541","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Author Michael Pollan had always been curious about psychoactive plants, but his interest skyrocketed when he heard about a \u003ca href=\"https://www.npr.org/sections/health-shots/2016/12/03/504136736/how-a-psychedelic-drug-helps-cancer-patients-overcome-anxiety\" target=\"_blank\" rel=\"noopener\">research study\u003c/a> in which people with terminal cancer were given a psychedelic called \u003ca href=\"https://www.npr.org/tags/140958387/psilocybin\" target=\"_blank\" rel=\"noopener\">psilocybin \u003c/a>— the active ingredient in \"magic mushrooms\" — to help them deal with their distress.\u003c/p>\n\u003cp>\"This seemed like such a crazy idea that I began looking into it,\" Pollan says. \"Why should a drug from a mushroom help people deal with their mortality?\"\u003c/p>\n\u003cp>Pollan, whose previous books include \u003ca href=\"https://www.npr.org/books/titles/137946336/the-omnivores-dilemma-a-natural-history-of-four-meals\" target=\"_blank\" rel=\"noopener\">The Omnivore's Dilemma\u003c/a> and \u003ca href=\"https://www.npr.org/templates/story/story.php?storyId=17725932\" target=\"_blank\" rel=\"noopener\">In Defense Of Food\u003c/a>, started researching different experimental therapeutic uses of psychedelics, and found that the drugs were being used to treat depression, addiction and the fear of death.\u003c/p>\n\u003cp>Then he decided to go one step further: A self-described \"reluctant psychonaut,\" Pollan enlisted guides to help him experiment with LSD, psilocybin and 5-MeO-DMT, a substance in the venom of the Sonoran Desert toad.\u003c/p>\n\u003cp>Each of Pollan's experiences with psychedelics was preceded by worry and self-doubt. But, he says, \"I realized later that was my ego trying to convince me not to do this thing that was going to challenge my ego.\"\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Pollan's new book, \u003cem>How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence\u003c/em>, recounts his experiences with the drugs and also examines the history of psychedelics as well as their possible therapeutic uses.\u003c/p>\n\u003chr>\n\u003cp>\u003cstrong>Interview Highlights\u003c/strong>\u003c/p>\n\u003cp>\u003cstrong>On how the psychedelic psilocybin is administered in therapy for depression \u003c/strong>\u003c/p>\n\u003cp>The way [psilocybin is] being used is in a very controlled or guided setting. ... They don't just give you a pill and send you home; you're in a room. You're with two guides, one male, one female. You're lying down on a comfortable couch. You're wearing headphones listening to a really carefully curated playlist of music — instrumental compositions for the most part — and you're wearing eyeshades, all of which is to encourage a very inward journey.\u003c/p>\n\u003cp>Someone is kind of looking out for you, and they prepare you very carefully in advance. They give you a set of \"flight instructions,\" as they call them, which is what to do if you get really scared or you're beginning to have a bad trip. If you see a monster, for example, don't try to run away. Walk right up to it, plant your feet and say, \"What do you have to teach me? What are you doing in my mind?\" And if you do that, according to the flight instructions, your fear will morph into something much more positive very quickly.\u003c/p>\n\u003cp>\u003cstrong>On how psychedelics can help change the stories we tell about ourselves \u003c/strong>\u003c/p>\n\u003cp>The drugs foster new perspectives on old problems. One of the things our mind does is tell stories about ourselves. If you're depressed, you're being told a story perhaps that you're worthless, that no one could possibly love you, you're not worthy of love, that life will not get better. And these stories — which are enforced by our egos really — trap us in these ruminative loops that are very hard to get out of. They're very destructive patterns of thought.\u003c/p>\n\u003cp>What the drugs appear to do is disable for a period of time the part of the brain where the self talks to itself. It's called the \u003ca href=\"https://www.npr.org/tags/482443062/default-mode-network\" target=\"_blank\" rel=\"noopener\">default mode network\u003c/a>, and it's a group of structures that connect parts of the cortex — the evolutionarily most recent part of the brain — to deeper levels where emotion and memory reside. And it's a very important hub in the brain and lots of important things happen there: self-reflection and rumination, time travel. It's where we go to think about the future or the past, and theory of mind, the ability to imagine the mental states of other beings and, I think, most importantly, the autobiographical self. It's the part of the brain, it appears, where we incorporate things that happen to us, new information, with a sense of who we are, who we were and who we want to be. And that's where these stories get generated. And these stories can be really destructive, they trap us. ...\u003c/p>\n\u003cp>This network is downregulated [with psychedelics], it sort of goes offline for a period of time. And that's why you experience this dissolution of self or ego, which can be a terrifying or liberating thing, depending on your mindset. This is what allows people, I think, to have those new perspectives on themselves, to realize that they needn't be trapped in those stories and they might actually be able to write some new stories about themselves. That's what's liberating, I think, about the experience when it works.\u003c/p>\n\u003cp>\u003cstrong>On how psychedelics can help dying people face their deaths \u003c/strong>\u003c/p>\n\u003cp>\u003ca href=\"https://www.npr.org/tags/125941537/prozac\">Prozac\u003c/a> doesn't help when you're confronting your mortality. But here we have something that occasions an experience in people — a mystical experience — that somehow makes it easier to let go. And I think some of it has to do with the fact that you do experience the \"extinction\" of yourself and it's kind of a rehearsal for death. And I think that may be part of what helps people, that they expand their sense of what is your self-interest and your self-interest is something larger than what is contained by your skin. And when you have that recognition, I think dying becomes a little easier. ...\u003c/p>\n\u003cp>There's no way to prove this, obviously, and it's a question that really troubled me as an old-fashioned materialist skeptical journalist. It's like, \"What if these drugs are inducing an illusion in people?\" I got a variety of answers to that question from the researchers. One was, \"Who cares if it helps them?\" And I can see the point of that. The other was, \"Hey, this is beyond my pay grade; none of us know what happens after we die.\" And others say, \"Well, this is an open frontier.\" ...\u003c/p>\n\u003cp>The experiences that people have are very real to them — they're psychological facts. And one of the really interesting qualities of psychedelic experience is that the insights you have on them have a durability ... This isn't just an opinion, this is revealed truth, so the confidence people have is hard to shake, actually.\u003c/p>\n\u003cp>\u003cstrong>On a \u003c/strong>\u003ca href=\"https://www.hopkinsmedicine.org/news/stories/mushrooms_quit_smoking.html\" target=\"_blank\" rel=\"noopener\">\u003cstrong>Johns Hopkins study\u003c/strong>\u003c/a>\u003cstrong> on the use of psilocybin to help people quit smoking \u003c/strong>\u003c/p>\n\u003cp>Smoking is a very hard addiction to break. It's one of the hardest addictions to break. [I wanted to understand] how, after a single psilocybin trip, they could decide \"I'm never going to smoke again\" based on the perspective they had achieved. And they would say things like, \"Well, I had this amazing experience. I died three times. I sprouted wings. I flew through European histories. I beheld all these wonders. I saw my body on a funeral pyre on the Ganges. And I realized, the universe is so amazing and there's so much to do in it that killing myself seemed really stupid.\" And that was the insight. Yes, killing yourself is really stupid — but it had an authority it had never had. And that, I think, is the gift of these psychedelics.\u003c/p>\n\u003cp>\u003cstrong>On his own experience tripping on mushrooms \u003c/strong>\u003c/p>\n\u003cp>I had an experience that was by turns frightening and ecstatic and weird. ... I found myself in this place where I could no longer control my perceptions at all, and I felt my sense of self scatter to the wind — almost as if a pile of post-its had been released to the wind — but I was fine with it. I didn't feel any desire to pile the papers back together into my customary self ...\u003c/p>\n\u003cp>Then I looked out and saw myself spread over the landscape like a coat of paint or butter. I was outside myself, beside myself, literally, and the consciousness that beheld this ... was not my normal consciousness, it was completely unperturbed. It was dispassionate. It was content, as I watched myself dissolve over the landscape.\u003c/p>\n\u003cp>What I brought back from that experience was that I'm not identical to my ego, that there is another ground on which to plant our feet and that our ego is kind of this character that is chattering neurotically in our minds. And it's good for lots of things. I mean, the ego got the book written, but it also can be very harsh, and it's liberating to have some distance on it. And that was a great gift, I think.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003cem>Sam Briger and Seth Kelley produced and edited this interview for broadcast. Bridget Bentz, Molly Seavy-Nesper and Scott Hensley adapted it for the Web.\u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2018 Fresh Air. To see more, visit \u003ca href=\"http://www.npr.org/programs/fresh-air/\" target=\"_blank\" rel=\"noopener\">Fresh Air\u003c/a>.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=%27Reluctant+Psychonaut%27+Michael+Pollan+Embraces+The+%27New+Science%27+Of+Psychedelics+&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/441705/reluctant-psychonaut-michael-pollan-embraces-the-new-science-of-psychedelics","authors":["byline_futureofyou_441705"],"categories":["futureofyou_1060","futureofyou_1"],"tags":["futureofyou_56","futureofyou_952","futureofyou_1432"],"collections":["futureofyou_1093"],"featImg":"futureofyou_441707","label":"source_futureofyou_441705"},"futureofyou_437973":{"type":"posts","id":"futureofyou_437973","meta":{"index":"posts_1591205157","site":"futureofyou","id":"437973","score":null,"sort":[1514275314000]},"guestAuthors":[],"slug":"video-for-lsd-what-a-long-strange-trip-its-been","title":"VIDEO: For LSD, What A Long Strange Trip It's Been","publishDate":1514275314,"format":"standard","headTitle":"KQED Future of You | KQED Science","labelTerm":{"site":"futureofyou"},"content":"\u003cp>Psychedelic drugs are getting a makeover, with scientists exploring their potential in treating debilitating conditions like cluster headaches, addiction or anxiety, with promising results.\u003c/p>\n\u003cp>That's despite the fact that very few researchers are legally allowed to study psychedelics, largely because of LSD's decades-old reputation as a counterculture drug that sparked bad trips.\u003c/p>\n\u003cp>Back in the 1960s, LSD was touted as a tool to shed social conventions and fast-forward to enlightenment – or as LSD advocate Timothy Leary memorably said, \"Turn on, tune in, drop out.\"\u003c/p>\n\u003cp>[contextly_sidebar id=\"Y62bP7N4rAZf0wVWIiXnJDweibkHKwpr\"]He was hardly the first to feel the chemical's allure. Back in the 1930s, Swiss chemist Albert Hofmann had shelved LSD after first testing it as a treatment for heart disease. But he couldn't shake the feeling that there was something more to it. After accidentally ingesting a bit and having a mild psychedelic experience, Hofmann decided to go further.\u003c/p>\n\u003cp>He eats 250 micrograms of LSD and, scientist that he is, starts\u003ca href=\"https://www.maps.org/images/pdf/books/lsdmyproblemchild.pdf\"> journaling his experience\u003c/a>. He only gets one entry down before he starts having really intense hallucinations. As he bikes home, he feels like time and space are standing still and objects around him are warping and wavering in weird shapes.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>The next day, he writes, \"A sensation of well-being and renewed life flowed through me... everything glistened and sparkled in a fresh light.\"\u003c/p>\n\u003cp>LSD seems to shut off certain controls in the brain, allowing signals from one part of the brain to flow unchecked to other regions – particularly the regions that process sensory inputs from the outside world and the regions that define our sense of self. This might explain \u003ca href=\"https://www.npr.org/sections/health-shots/2016/04/13/474071268/how-lsd-makes-your-brain-one-with-the-universe\">why LSD can cause hallucinations\u003c/a>. It's also why it could plausibly be beneficial to treat depression or anxiety, allowing signals in the brain to bypass pathways that aren't working so well.\u003c/p>\n\u003cp>Years of experimentation with LSD both in the laboratory and as a recreational drug suggest that it is \u003ca href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747247/\">physically and mentally safe\u003c/a> for healthy individuals. But it can also bring on terrifying hallucinations and sensations, including anxiety and paranoia, especially if people aren't prepared for the experience.\u003c/p>\n\u003cp>In the 1950s, the \u003ca href=\"https://www.npr.org/sections/pictureshow/2010/12/01/131724898/lsd-testing\">U.S. Army\u003c/a> tested LSD's potential to incapacitate enemy soldiers, but it turned out to be too expensive and difficult to deliver by aerosol. The CIA also tested it as tool for mind control by administering it to people, sometimes illegally and without their knowledge or consent, in the notorious \u003ca href=\"https://www.npr.org/2017/03/28/521779864/inside-darpa-the-pentagon-agency-whose-technology-has-changed-the-world\">Project MKUltra\u003c/a>.\u003c/p>\n\u003cp>In the early 1960s, it was embraced by a growing counterculture movement searching for mind-altering experiences through art and music from groups like Jefferson Airplane and the Grateful Dead. LSD became simultaneously the most studied psychoactive drug in history and a leading cause for young people ending up in the emergency room. When the federal government \u003ca href=\"https://www.npr.org/sections/health-shots/2016/04/13/474071268/how-lsd-makes-your-brain-one-with-the-universe\">banned LSD\u003c/a> as a dangerous drug in 1971, it also restricted any further research on the drug and other known psychedelics.\u003c/p>\n\u003cp>But scientists hadn't forgotten its early promise.\u003c/p>\n\u003cp>Researchers have successfully fought for approval to study LSD, as well as other psychedelics such as psilocybin (the active compound in magic mushrooms) and MDMA, also known as the club drug ecstasy.\u003c/p>\n\u003cp>Carefully controlled studies have shown that LSD helps relieve debilitating cluster headaches, that \u003ca href=\"https://www.npr.org/sections/health-shots/2016/12/03/504136736/how-a-psychedelic-drug-helps-cancer-patients-overcome-anxiety\">psilocybin alleviates depression\u003c/a> in terminal cancer patients, and that \u003ca href=\"https://www.npr.org/2015/09/13/439963019/researchers-turn-to-popular-club-drug-to-treat-ptsd\">MDMA can help relieve the trauma of PTSD\u003c/a>. Earlier this year, the FDA gave MDMA a \"\u003ca href=\"https://www.maps.org/news/media/6786-press-release-fda-grants-breakthrough-therapy-designation-for-mdma-assisted-psychotherapy-for-ptsd,-agrees-on-special-protocol-assessment-for-phase-3-trials\">breakthrough therapy\u003c/a>\" designation, fast-tracking its path to Phase 3 clinical trials and and if all goes well, approval as a legal treatment.\u003c/p>\n\u003cp>\u003cem>Angus Chen is a journalist in New York. He's on Twitter @angrchen.\u003c/em>\u003c/p>\n\u003cp>\u003cem>Freddy Arenas is an \u003ca href=\"http://www.freddyarenas.com/\">independent director\u003c/a> who has created animations for \u003c/em>The New York Times, California Sunday Magazine\u003cem>,\u003c/em> Google\u003cem> and \u003c/em>HBO Documentaries\u003cem>.\u003c/em>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem> Meredith Rizzo produced this animation for NPR.\u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2017 NPR. To see more, visit http://www.npr.org/.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=VIDEO%3A+For+LSD%2C+What+A+Long+Strange+Trip+It%27s+Been&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n","blocks":[],"excerpt":"It's been reviled and revered, criminalized and exploited by the CIA. And now and other psychedelic drugs are being tested as legitimate medical treatments. NPR's original animation tells the tale.","status":"publish","parent":0,"modified":1514396393,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":18,"wordCount":650},"headData":{"title":"VIDEO: For LSD, What A Long Strange Trip It's Been | KQED","description":"It's been reviled and revered, criminalized and exploited by the CIA. And now and other psychedelic drugs are being tested as legitimate medical treatments. NPR's original animation tells the tale.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"VIDEO: For LSD, What A Long Strange Trip It's Been","datePublished":"2017-12-26T08:01:54.000Z","dateModified":"2017-12-27T17:39:53.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"437973 https://ww2.kqed.org/futureofyou/?p=437973","disqusUrl":"https://ww2.kqed.org/futureofyou/2017/12/26/video-for-lsd-what-a-long-strange-trip-its-been/","disqusTitle":"VIDEO: For LSD, What A Long Strange Trip It's Been","nprByline":"Angus Chen\u003cbr />NPR Shots","nprImageAgency":"Freddy Arenas for NPR","nprStoryId":"571123483","nprApiLink":"http://api.npr.org/query?id=571123483&apiKey=MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004","nprHtmlLink":"https://www.npr.org/sections/health-shots/2017/12/16/571123483/video-for-lsd-what-a-long-strange-trip-its-been?ft=nprml&f=571123483","nprRetrievedStory":"1","nprPubDate":"Tue, 19 Dec 2017 11:41:00 -0500","nprStoryDate":"Sat, 16 Dec 2017 07:00:00 -0500","nprLastModifiedDate":"Tue, 19 Dec 2017 11:41:24 -0500","path":"/futureofyou/437973/video-for-lsd-what-a-long-strange-trip-its-been","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Psychedelic drugs are getting a makeover, with scientists exploring their potential in treating debilitating conditions like cluster headaches, addiction or anxiety, with promising results.\u003c/p>\n\u003cp>That's despite the fact that very few researchers are legally allowed to study psychedelics, largely because of LSD's decades-old reputation as a counterculture drug that sparked bad trips.\u003c/p>\n\u003cp>Back in the 1960s, LSD was touted as a tool to shed social conventions and fast-forward to enlightenment – or as LSD advocate Timothy Leary memorably said, \"Turn on, tune in, drop out.\"\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003c/p>\u003cp>He was hardly the first to feel the chemical's allure. Back in the 1930s, Swiss chemist Albert Hofmann had shelved LSD after first testing it as a treatment for heart disease. But he couldn't shake the feeling that there was something more to it. After accidentally ingesting a bit and having a mild psychedelic experience, Hofmann decided to go further.\u003c/p>\n\u003cp>He eats 250 micrograms of LSD and, scientist that he is, starts\u003ca href=\"https://www.maps.org/images/pdf/books/lsdmyproblemchild.pdf\"> journaling his experience\u003c/a>. He only gets one entry down before he starts having really intense hallucinations. As he bikes home, he feels like time and space are standing still and objects around him are warping and wavering in weird shapes.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>The next day, he writes, \"A sensation of well-being and renewed life flowed through me... everything glistened and sparkled in a fresh light.\"\u003c/p>\n\u003cp>LSD seems to shut off certain controls in the brain, allowing signals from one part of the brain to flow unchecked to other regions – particularly the regions that process sensory inputs from the outside world and the regions that define our sense of self. This might explain \u003ca href=\"https://www.npr.org/sections/health-shots/2016/04/13/474071268/how-lsd-makes-your-brain-one-with-the-universe\">why LSD can cause hallucinations\u003c/a>. It's also why it could plausibly be beneficial to treat depression or anxiety, allowing signals in the brain to bypass pathways that aren't working so well.\u003c/p>\n\u003cp>Years of experimentation with LSD both in the laboratory and as a recreational drug suggest that it is \u003ca href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747247/\">physically and mentally safe\u003c/a> for healthy individuals. But it can also bring on terrifying hallucinations and sensations, including anxiety and paranoia, especially if people aren't prepared for the experience.\u003c/p>\n\u003cp>In the 1950s, the \u003ca href=\"https://www.npr.org/sections/pictureshow/2010/12/01/131724898/lsd-testing\">U.S. Army\u003c/a> tested LSD's potential to incapacitate enemy soldiers, but it turned out to be too expensive and difficult to deliver by aerosol. The CIA also tested it as tool for mind control by administering it to people, sometimes illegally and without their knowledge or consent, in the notorious \u003ca href=\"https://www.npr.org/2017/03/28/521779864/inside-darpa-the-pentagon-agency-whose-technology-has-changed-the-world\">Project MKUltra\u003c/a>.\u003c/p>\n\u003cp>In the early 1960s, it was embraced by a growing counterculture movement searching for mind-altering experiences through art and music from groups like Jefferson Airplane and the Grateful Dead. LSD became simultaneously the most studied psychoactive drug in history and a leading cause for young people ending up in the emergency room. When the federal government \u003ca href=\"https://www.npr.org/sections/health-shots/2016/04/13/474071268/how-lsd-makes-your-brain-one-with-the-universe\">banned LSD\u003c/a> as a dangerous drug in 1971, it also restricted any further research on the drug and other known psychedelics.\u003c/p>\n\u003cp>But scientists hadn't forgotten its early promise.\u003c/p>\n\u003cp>Researchers have successfully fought for approval to study LSD, as well as other psychedelics such as psilocybin (the active compound in magic mushrooms) and MDMA, also known as the club drug ecstasy.\u003c/p>\n\u003cp>Carefully controlled studies have shown that LSD helps relieve debilitating cluster headaches, that \u003ca href=\"https://www.npr.org/sections/health-shots/2016/12/03/504136736/how-a-psychedelic-drug-helps-cancer-patients-overcome-anxiety\">psilocybin alleviates depression\u003c/a> in terminal cancer patients, and that \u003ca href=\"https://www.npr.org/2015/09/13/439963019/researchers-turn-to-popular-club-drug-to-treat-ptsd\">MDMA can help relieve the trauma of PTSD\u003c/a>. Earlier this year, the FDA gave MDMA a \"\u003ca href=\"https://www.maps.org/news/media/6786-press-release-fda-grants-breakthrough-therapy-designation-for-mdma-assisted-psychotherapy-for-ptsd,-agrees-on-special-protocol-assessment-for-phase-3-trials\">breakthrough therapy\u003c/a>\" designation, fast-tracking its path to Phase 3 clinical trials and and if all goes well, approval as a legal treatment.\u003c/p>\n\u003cp>\u003cem>Angus Chen is a journalist in New York. He's on Twitter @angrchen.\u003c/em>\u003c/p>\n\u003cp>\u003cem>Freddy Arenas is an \u003ca href=\"http://www.freddyarenas.com/\">independent director\u003c/a> who has created animations for \u003c/em>The New York Times, California Sunday Magazine\u003cem>,\u003c/em> Google\u003cem> and \u003c/em>HBO Documentaries\u003cem>.\u003c/em>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003cem> Meredith Rizzo produced this animation for NPR.\u003c/em>\u003c/p>\n\u003cdiv class=\"fullattribution\">Copyright 2017 NPR. To see more, visit http://www.npr.org/.\u003cimg src=\"https://www.google-analytics.com/__utm.gif?utmac=UA-5828686-4&utmdt=VIDEO%3A+For+LSD%2C+What+A+Long+Strange+Trip+It%27s+Been&utme=8(APIKey)9(MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004)\">\u003c/div>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/futureofyou/437973/video-for-lsd-what-a-long-strange-trip-its-been","authors":["byline_futureofyou_437973"],"categories":["futureofyou_1"],"tags":["futureofyou_1431","futureofyou_1432","futureofyou_1430"],"featImg":"futureofyou_437974","label":"futureofyou"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. 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You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. This podcast feed is usually updated twice a week and is always un-edited.","airtime":"THU 10pm, FRI 1am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Commonwealth-Club-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.commonwealthclub.org/podcasts","meta":{"site":"news","source":"Commonwealth Club of California"},"link":"/radio/program/commonwealth-club","subscribe":{"apple":"https://itunes.apple.com/us/podcast/commonwealth-club-of-california-podcast/id976334034?mt=2","google":"https://podcasts.google.com/feed/aHR0cDovL3d3dy5jb21tb253ZWFsdGhjbHViLm9yZy9hdWRpby9wb2RjYXN0L3dlZWtseS54bWw","tuneIn":"https://tunein.com/radio/Commonwealth-Club-of-California-p1060/"}},"considerthis":{"id":"considerthis","title":"Consider This","tagline":"Make sense of the day","info":"Make sense of the day. Every weekday afternoon, Consider This helps you consider the major stories of the day in less than 15 minutes, featuring the reporting and storytelling resources of NPR. Plus, KQED’s Bianca Taylor brings you the local KQED news you need to know.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Consider-This-Podcast-Tile-703x703-1.jpg","imageAlt":"Consider This from NPR and KQED","officialWebsiteLink":"/podcasts/considerthis","meta":{"site":"news","source":"kqed","order":"7"},"link":"/podcasts/considerthis","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1503226625?mt=2&at=11l79Y&ct=nprdirectory","npr":"https://rpb3r.app.goo.gl/coronavirusdaily","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM1NS9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/3Z6JdCS2d0eFEpXHKI6WqH"}},"forum":{"id":"forum","title":"Forum","tagline":"The conversation starts here","info":"KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.","airtime":"MON-FRI 9am-11am, 10pm-11pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Forum-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Forum with Mina Kim and Alexis Madrigal","officialWebsiteLink":"/forum","meta":{"site":"news","source":"kqed","order":"8"},"link":"/forum","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-forum/id73329719","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5NTU3MzgxNjMz","npr":"https://www.npr.org/podcasts/432307980/forum","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-forum-podcast","rss":"https://feeds.megaphone.fm/KQINC9557381633"}},"freakonomics-radio":{"id":"freakonomics-radio","title":"Freakonomics Radio","info":"Freakonomics Radio is a one-hour award-winning podcast and public-radio project hosted by Stephen Dubner, with co-author Steve Levitt as a regular guest. 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