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"slug": "a-year-after-ingesting-someone-elses-feces-biohacker-feels-like-a-new-man",
"title": "After Ingesting Someone Else's Feces, Biohacker Feels Like New Man",
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"content": "\u003cp>If you were a former NASA scientist and current biohacker afflicted with severe and irresolvable gastrointestinal woes, what would you do?\u003c/p>\n\u003cp>(a) Live with the problem as best you could\u003cbr>\n(b) Attempt to replace all the bacteria in your body by taking antibiotics then swallowing a capsule of someone else’s poop\u003c/p>\n\u003caside class=\"pullquote alignright\">An experiment no one recommends: Killing your bacteria with antibiotics, then performing a fecal transplant on yourself.\u003c/aside>\n\u003cp>The correct answer — well, it isn’t (a). Not if you’re Josiah Zayner.\u003c/p>\n\u003cp>Zayner’s experiment was the subject of a short New York Times \u003ca href=\"https://www.nytimes.com/video/opinion/100000005015342/gut-hack.html\" target=\"_blank\" rel=\"noopener noreferrer\">documentary\u003c/a> last month and it is pretty interesting, to say the least. (Disclosure: Danielle Venton was acquainted with one of the filmmakers in high school.)\u003c/p>\n\u003cp>\u003c!-- iframe plugin v.4.3 wordpress.org/plugins/iframe/ -->\u003cbr>\n\u003ciframe loading=\"lazy\" width=\"640\" height=\"361\" src=\"//static01.nyt.com/video/players/offsite/index.html?videoId=100000005015342\" frameborder=\"0\" scrolling=\"no\" class=\"iframe-class\">\u003c/iframe>\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\u003ca href=\"#interview\">See below for our interview with Zayner\u003c/a>, a year after the experiment. Future of You first met the mid-30s, erstwhile NASA Ames bio-researcher, upon the launch of his business, providing \u003ca href=\"https://ww2.kqed.org/futureofyou/2016/02/22/gene-editing-coming-to-a-kitchen-counter-near-you/\" target=\"_blank\" rel=\"noopener noreferrer\">in-home CRISPR/Cas9 gene-editing kits\u003c/a> to the public. That was\u003ca href=\"https://www.digitaltrends.com/cool-tech/the-odin-diy-crispr-kit/\" target=\"_blank\" rel=\"noopener noreferrer\"> controversial\u003c/a> enough.\u003c/p>\n\u003cp>Then last May, Zayner, who has suffered from ulcers, irritable bowel syndrome and frequent diarrhea that have not responded well to conventional treatments, decided to take matters into his own hands — or guts — in an attempt to replace his microbiome and mitigate his bad GI problems.\u003c/p>\n\u003cp>Bacteria are “almost an extension of you that can be helpful or harmful,” Zayner says. “It’s like this moving cloud that comes with you wherever you go. We and bacteria are like one organism.”\u003c/p>\n\u003cp>Watch the video and you’ll see him replacing part of that organism by taking antibiotics to eradicate his own bacteria, then ingesting the feces of a friend (“\u003ca href=\"http://www.urbandictionary.com/define.php?term=Yolo\" target=\"_blank\" rel=\"noopener noreferrer\">Yolo\u003c/a>,” he says at the moment of truth, the biohacker equivalent of “Down the hatch.”) He also swabbed his body and mouth with a saline solution containing the donor’s bacteria.\u003c/p>\n\u003cp>\u003ca href=\"https://ww2.kqed.org/futureofyou/2015/06/15/in-future-fecal-transplants-the-tool-wont-be-stool/\" target=\"_blank\" rel=\"noopener noreferrer\">Fecal transplants\u003c/a> are now an accepted therapy for a certain type of infection. The thing is, Zayner didn’t bother to test his donor’s sample. That puts him at risk, as the documentary warns, for “\u003cspan class=\"s1\">transference of parasites and pathogens, and even blood-borne illnesses like hepatitis.”\u003c/span>\u003c/p>\n\u003cp class=\"p1\">“S\u003cspan class=\"s1\">ometimes there’s this thin line, you know, between being crazy and being knowledgeable,” Zayner admits. “And I can’t tell.”\u003c/span>\u003c/p>\n\u003cp class=\"p1\">The Verge covered the experiment at the time. Writer Arielle Duhaime-Ross thought the process was less than scientifically rigid:\u003c/p>\n\u003cblockquote>\n\u003cp class=\"p1\">I couldn’t help but notice Zayner cutting corners. After drying off, he put on a brand-new Hanes white T-shirt to prevent his old microbiome from recolonizing his body, but an old — though freshly laundered — pair of jeans. He sampled his arms, nose, and mouth, but he didn’t bother to take microbial samples from his genitalia, and didn’t plan on applying Michael’s skin bacteria to his penis or testicles. He told me that there just isn’t much scientific value in gathering that information. Over the course of his experiment, Zayner would only take a third of the poop pills that someone undergoing a standard FMT [Fecal Microbiota Transplantation\u003cem>] \u003c/em>procedure would, stretched over a longer period of time.\u003c/p>\n\u003c/blockquote>\n\u003cp class=\"p1\">Says a podcaster from The Verge: “T\u003cspan class=\"s1\">his guy is doing something that is legitimately dangerous and probably kind of stupid.”\u003c/span>\u003c/p>\n\u003cp class=\"p1\">The experiment, according to Zayner, as well as genetic sequencing from an independent lab, was at least a partial success. (But need we say it: Don’t try this at home.)\u003ca id=\"interview\">\u003c/a>\u003c/p>\n\u003cp>Now that about a year has passed, we wanted to catch up with Zayner to see how he’s feeling about his health, the procedure and his critics. The following has been edited for length and clarity.\u003c/p>\n\u003cp>\u003cstrong>In the video, that did not look too fun.\u003c/strong>\u003c/p>\n\u003cp>Yeah. The original plan wasn’t to have people document it. I was going to document it myself. But other people got involved, including a reporter and the people who made the documentary. So in the hotel room there’s like four other people that you can’t see who are badgering me with questions, taking pictures, and I’m just like ‘Oh my gosh, I just feel sick. Can’t you people leave me alone?’ ”\u003c/p>\n\u003cp>\u003cstrong>How are you feeling now?\u003c/strong>\u003c/p>\n\u003cp>I was really amazed by the results. There’s been no blood in my stool since the transplant, which just kind of blows me away; prior to the transplant it had been multiple times a week.\u003c/p>\n\u003cp>\u003cstrong>While the transfer of the gut microbes seemed to be successful , the bacteria in your skin and nasal passages were unchanged. Why do you think that is? \u003c/strong>\u003c/p>\n\u003cp>I think I was recolonized by my own bacteria when I got back home to my own apartment.\u003c/p>\n\u003cp>\u003cstrong>Have you noticed any personality or mood changes? \u003c/strong>\u003c/p>\n\u003cp>I asked people close to me to say if they saw any changes. It doesn’t seem like there’s anything aside from an addiction-level sugar craving. I’ve never encountered a craving like this. At first I didn’t fight against it. I’d go to the grocery store and find myself buying 50 candy bars.\u003c/p>\n\u003cp>\u003cstrong>Does your donor friend have a sweet-tooth? \u003c/strong>\u003c/p>\n\u003cp>I asked him if he had sugar cravings, too, and he said, “I could eat a box of Oreos in one sitting.”\u003c/p>\n\u003cp>\u003cstrong>Have any microbiome researchers reached out to you? \u003c/strong>\u003c/p>\n\u003cp>A ton, but none of them want me to mention their name or talk about them publicly — people from MIT, UCLA, Harvard, University of Chicago, UC Irvine, UC Davis, the FDA. They might be a little bit critical, but they’re mostly interested.\u003c/p>\n\u003cp>\u003cstrong>Have you heard of other people trying this? Is that a concern, or even a hope of yours?\u003c/strong>\u003c/p>\n\u003cp>It is a little bit of a concern, because what I did was pretty drastic. I wasn’t just trying to do a fecal transplant. I was trying to do a whole-body microbiome transplant.\u003cstrong> \u003c/strong>\u003c/p>\n\u003cp>\u003cstrong>You weren’t just trying to supplement, you were trying to wipe out and replace… \u003c/strong>\u003c/p>\n\u003cp>A lot of people focused just on the fecal transplant. And that was the thing that provided the greatest benefit to me and worked. But I was also trying as hard as I could to wipe out all of the bacteria on my body and in my body, which — most people thought I would either die or end up hospitalized, which is crazy. That didn’t happen.\u003c/p>\n\u003cp>\u003cstrong>But were you worried about safety?\u003c/strong>\u003c/p>\n\u003cp>Based upon my planning, I thought the chances of something bad happening\u003cstrong> \u003c/strong>were pretty small. But when you have a lot of people around…mostly the people who were documenting it were really worried about a lot of things. Their attitude rubbed off on me and I got more and more worried.\u003c/p>\n\u003cp>\u003cstrong>The donor’s samples — why didn’t you have those tested for things that could be dangerous?\u003c/strong>\u003c/p>\n\u003cp>I really thought about that. A part of it might have been foolhardy, but part of me was like the whole purpose of this experiment was to create an idea of how somebody could do something like this. A lot of people don’t have access to getting donors tested.\u003c/p>\n\u003cp>I thought the process I went through was pretty stringent. If you go to \u003ca href=\"http://www.openbiome.org/\" target=\"_blank\" rel=\"noopener noreferrer\">OpenBiome\u003c/a>, the website that takes fecal transplants from people and they freeze them to give to people, they have a questionnaire you can fill out to see if you qualify as a donor. It’s pretty extensive and it’s something I mimicked.\u003c/p>\n\u003cp>The major things that you’re probably worried about are more blood-borne diseases and illnesses. People always say you should be afraid of feces because of hemorrhagic E. coli. Honestly, I don’t think there is anybody who has hemorrhagic E. coli colonizing them and doesn’t know about it. So I wasn’t too concerned about that.\u003c/p>\n\u003cp>Maybe this sounds crazy, but there is a certain amount of trust that you want to be able to place in humanity or other people.\u003c/p>\n\u003cp>\u003cstrong>The donor was also your \u003cem>friend\u003c/em>. \u003c/strong>\u003c/p>\n\u003cp>Totally. It was kind of symbolic in that way. If I can’t trust this person, then we’re all screwed.\u003c/p>\n\u003cp>\u003cstrong>You said you want this kind of experiment to be accessible to people. Is that because you want people to be able to understand it easily, or do you see this as a prototype?\u003c/strong>\u003c/p>\n\u003cp>Kind of a prototype, but you have to understand, I don’t recommend this to people.\u003c/p>\n\u003cp>The position I’m in right now is really strange where I’ve become this “biohacker” figure. I get contacted by a ton of people all the time, and a lot of those are people with medical issues. And they have no treatment, no cure, and they’re just looking for help. They’re looking for some way they can treat themselves.\u003c/p>\n\u003cp>The U.S. unfortunately has decided to not allow doctors to prescribe feces to people for any disease other than Clostridium difficile infections that haven’t been able to be treated with antibiotics.\u003c/p>\n\u003cp>To me, that’s kind of disturbing. And the fact that people have the opportunity to seek treatment themselves, I think, is empowering. So what I really wanted to do was say, “Hey look, I tried to do something in a very scientific way. And I’m not saying it works, I’m not saying it’ll work for you or your disease or cure your ailments at all. But maybe you can also try to take your health into your own hands. Maybe if there’s no hope from the medical community, no hope for cures, you can perhaps figure out something on your own — through experimentation, through reading scientific papers — and help yourself.\u003c/p>\n\u003cp>\u003cstrong>The podcasters at \u003cem>The Verge \u003c/em>had some pretty harsh words for you. What did you think about that? \u003c/strong>\u003c/p>\n\u003cp>You know, I understand from a professional point of view what they were trying to do. But some of the stuff they said just cracked me up.\u003c/p>\n\u003cp>They said that what I was doing was stupid — which is hilarious when you’re talking about a person who is suffering from something. It’s like, “Hey, you’re suffering from some problem and I think you trying to help yourself is the stupidest thing you could do.”\u003c/p>\n\u003cp>They don’t know what it’s like when you have to go to the bathroom five times in an hour and\u003cb> \u003c/b>blood is spewing out of your butt and you’re in terrible pain.\u003c/p>\n\u003cp>People always bring up this issue about whether what I did was “scientific” or not. That critique is very dogmatic about the way that science is or should be done. What’s important about what I did was whether it works or not, right? I mean, if this actually worked, why wouldn’t people be interested? And look, I’m not trying to publish any of this, I’m not trying to have it peer-reviewed in any normal terms.\u003c/p>\n\u003cp>\u003cstrong>But you would like it if people took a look at what you did and said, ‘Maybe there’s something here.’\u003c/strong>\u003c/p>\n\u003cp>Yeah, but I think they know there is. There are clinics oversees, in the UK and other places that actually will give fecal transplants to people suffering from gastrointestinal illness. It’s something interesting that in the U.S. isn’t allowed.\u003c/p>\n\u003chr>\n\u003cp>We reached out to a handful of microbiome researchers for their thoughts on Zayner’s experiment. One, Owen White from the University of Maryland School of Medicine, responded.\u003c/p>\n\u003cp>“If I had a molecular biology background and was suffering from problems like Josiah, I would find it irresistible not to want to at least try some type of intervention on myself,” wrote White in an email.\u003c/p>\n\u003cp>“(T)here is something inherently deserving about exerting your own agency over things that you cannot ordinarily control,” White said. “That being said, I strongly agree with all the criticisms that were shown in the video.”\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>\u003cem>For more, see Josiah Zayner’s \u003ca href=\"http://www.ifyoudontknownowyaknow.com/2016/05/i-transplanted-someone-elses-microbiome.html\" target=\"_blank\" rel=\"noopener noreferrer\">blog post about the transplant\u003c/a>, his \u003ca href=\"https://www.reddit.com/r/IAmA/comments/4i5euw/im_dr_josiah_zayner_former_scientist_at_nasa/\" target=\"_blank\" rel=\"noopener noreferrer\">AmA (Ask me Anything) entry on Reddit\u003c/a> or Arielle Duhaime-Ross’s \u003ca href=\"https://www.theverge.com/2016/5/4/11581994/fmt-fecal-matter-transplant-josiah-zayner-microbiome-ibs-c-diff\" target=\"_blank\" rel=\"noopener noreferrer\">coverage for The Verge\u003c/a>.\u003c/em>\u003c/p>\n\n",
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"excerpt": "Catching up with Josiah Zayner, the biohacker who attempted to replace his microbiome as part of an experiment to help irresolvable gastrointestinal woes. And need we say it: Don't try this at home.",
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"title": "After Ingesting Someone Else’s Feces, Biohacker Feels Like New Man",
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"headline": "After Ingesting Someone Else's Feces, Biohacker Feels Like New Man",
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"content": "\u003cdiv class=\"post-body\">\u003cp>\u003cp>If you were a former NASA scientist and current biohacker afflicted with severe and irresolvable gastrointestinal woes, what would you do?\u003c/p>\n\u003cp>(a) Live with the problem as best you could\u003cbr>\n(b) Attempt to replace all the bacteria in your body by taking antibiotics then swallowing a capsule of someone else’s poop\u003c/p>\n\u003caside class=\"pullquote alignright\">An experiment no one recommends: Killing your bacteria with antibiotics, then performing a fecal transplant on yourself.\u003c/aside>\n\u003cp>The correct answer — well, it isn’t (a). Not if you’re Josiah Zayner.\u003c/p>\n\u003cp>Zayner’s experiment was the subject of a short New York Times \u003ca href=\"https://www.nytimes.com/video/opinion/100000005015342/gut-hack.html\" target=\"_blank\" rel=\"noopener noreferrer\">documentary\u003c/a> last month and it is pretty interesting, to say the least. (Disclosure: Danielle Venton was acquainted with one of the filmmakers in high school.)\u003c/p>\n\u003cp>\u003c!-- iframe plugin v.4.3 wordpress.org/plugins/iframe/ -->\u003cbr>\n\u003ciframe loading=\"lazy\" width=\"640\" height=\"361\" src=\"//static01.nyt.com/video/players/offsite/index.html?videoId=100000005015342\" frameborder=\"0\" scrolling=\"no\" class=\"iframe-class\">\u003c/iframe>\u003c/p>\n\u003cp>\u003c/p>\u003c/div>",
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"content": "\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003ca href=\"#interview\">See below for our interview with Zayner\u003c/a>, a year after the experiment. Future of You first met the mid-30s, erstwhile NASA Ames bio-researcher, upon the launch of his business, providing \u003ca href=\"https://ww2.kqed.org/futureofyou/2016/02/22/gene-editing-coming-to-a-kitchen-counter-near-you/\" target=\"_blank\" rel=\"noopener noreferrer\">in-home CRISPR/Cas9 gene-editing kits\u003c/a> to the public. That was\u003ca href=\"https://www.digitaltrends.com/cool-tech/the-odin-diy-crispr-kit/\" target=\"_blank\" rel=\"noopener noreferrer\"> controversial\u003c/a> enough.\u003c/p>\n\u003cp>Then last May, Zayner, who has suffered from ulcers, irritable bowel syndrome and frequent diarrhea that have not responded well to conventional treatments, decided to take matters into his own hands — or guts — in an attempt to replace his microbiome and mitigate his bad GI problems.\u003c/p>\n\u003cp>Bacteria are “almost an extension of you that can be helpful or harmful,” Zayner says. “It’s like this moving cloud that comes with you wherever you go. We and bacteria are like one organism.”\u003c/p>\n\u003cp>Watch the video and you’ll see him replacing part of that organism by taking antibiotics to eradicate his own bacteria, then ingesting the feces of a friend (“\u003ca href=\"http://www.urbandictionary.com/define.php?term=Yolo\" target=\"_blank\" rel=\"noopener noreferrer\">Yolo\u003c/a>,” he says at the moment of truth, the biohacker equivalent of “Down the hatch.”) He also swabbed his body and mouth with a saline solution containing the donor’s bacteria.\u003c/p>\n\u003cp>\u003ca href=\"https://ww2.kqed.org/futureofyou/2015/06/15/in-future-fecal-transplants-the-tool-wont-be-stool/\" target=\"_blank\" rel=\"noopener noreferrer\">Fecal transplants\u003c/a> are now an accepted therapy for a certain type of infection. The thing is, Zayner didn’t bother to test his donor’s sample. That puts him at risk, as the documentary warns, for “\u003cspan class=\"s1\">transference of parasites and pathogens, and even blood-borne illnesses like hepatitis.”\u003c/span>\u003c/p>\n\u003cp class=\"p1\">“S\u003cspan class=\"s1\">ometimes there’s this thin line, you know, between being crazy and being knowledgeable,” Zayner admits. “And I can’t tell.”\u003c/span>\u003c/p>\n\u003cp class=\"p1\">The Verge covered the experiment at the time. Writer Arielle Duhaime-Ross thought the process was less than scientifically rigid:\u003c/p>\n\u003cblockquote>\n\u003cp class=\"p1\">I couldn’t help but notice Zayner cutting corners. After drying off, he put on a brand-new Hanes white T-shirt to prevent his old microbiome from recolonizing his body, but an old — though freshly laundered — pair of jeans. He sampled his arms, nose, and mouth, but he didn’t bother to take microbial samples from his genitalia, and didn’t plan on applying Michael’s skin bacteria to his penis or testicles. He told me that there just isn’t much scientific value in gathering that information. Over the course of his experiment, Zayner would only take a third of the poop pills that someone undergoing a standard FMT [Fecal Microbiota Transplantation\u003cem>] \u003c/em>procedure would, stretched over a longer period of time.\u003c/p>\n\u003c/blockquote>\n\u003cp class=\"p1\">Says a podcaster from The Verge: “T\u003cspan class=\"s1\">his guy is doing something that is legitimately dangerous and probably kind of stupid.”\u003c/span>\u003c/p>\n\u003cp class=\"p1\">The experiment, according to Zayner, as well as genetic sequencing from an independent lab, was at least a partial success. (But need we say it: Don’t try this at home.)\u003ca id=\"interview\">\u003c/a>\u003c/p>\n\u003cp>Now that about a year has passed, we wanted to catch up with Zayner to see how he’s feeling about his health, the procedure and his critics. The following has been edited for length and clarity.\u003c/p>\n\u003cp>\u003cstrong>In the video, that did not look too fun.\u003c/strong>\u003c/p>\n\u003cp>Yeah. The original plan wasn’t to have people document it. I was going to document it myself. But other people got involved, including a reporter and the people who made the documentary. So in the hotel room there’s like four other people that you can’t see who are badgering me with questions, taking pictures, and I’m just like ‘Oh my gosh, I just feel sick. Can’t you people leave me alone?’ ”\u003c/p>\n\u003cp>\u003cstrong>How are you feeling now?\u003c/strong>\u003c/p>\n\u003cp>I was really amazed by the results. There’s been no blood in my stool since the transplant, which just kind of blows me away; prior to the transplant it had been multiple times a week.\u003c/p>\n\u003cp>\u003cstrong>While the transfer of the gut microbes seemed to be successful , the bacteria in your skin and nasal passages were unchanged. Why do you think that is? \u003c/strong>\u003c/p>\n\u003cp>I think I was recolonized by my own bacteria when I got back home to my own apartment.\u003c/p>\n\u003cp>\u003cstrong>Have you noticed any personality or mood changes? \u003c/strong>\u003c/p>\n\u003cp>I asked people close to me to say if they saw any changes. It doesn’t seem like there’s anything aside from an addiction-level sugar craving. I’ve never encountered a craving like this. At first I didn’t fight against it. I’d go to the grocery store and find myself buying 50 candy bars.\u003c/p>\n\u003cp>\u003cstrong>Does your donor friend have a sweet-tooth? \u003c/strong>\u003c/p>\n\u003cp>I asked him if he had sugar cravings, too, and he said, “I could eat a box of Oreos in one sitting.”\u003c/p>\n\u003cp>\u003cstrong>Have any microbiome researchers reached out to you? \u003c/strong>\u003c/p>\n\u003cp>A ton, but none of them want me to mention their name or talk about them publicly — people from MIT, UCLA, Harvard, University of Chicago, UC Irvine, UC Davis, the FDA. They might be a little bit critical, but they’re mostly interested.\u003c/p>\n\u003cp>\u003cstrong>Have you heard of other people trying this? Is that a concern, or even a hope of yours?\u003c/strong>\u003c/p>\n\u003cp>It is a little bit of a concern, because what I did was pretty drastic. I wasn’t just trying to do a fecal transplant. I was trying to do a whole-body microbiome transplant.\u003cstrong> \u003c/strong>\u003c/p>\n\u003cp>\u003cstrong>You weren’t just trying to supplement, you were trying to wipe out and replace… \u003c/strong>\u003c/p>\n\u003cp>A lot of people focused just on the fecal transplant. And that was the thing that provided the greatest benefit to me and worked. But I was also trying as hard as I could to wipe out all of the bacteria on my body and in my body, which — most people thought I would either die or end up hospitalized, which is crazy. That didn’t happen.\u003c/p>\n\u003cp>\u003cstrong>But were you worried about safety?\u003c/strong>\u003c/p>\n\u003cp>Based upon my planning, I thought the chances of something bad happening\u003cstrong> \u003c/strong>were pretty small. But when you have a lot of people around…mostly the people who were documenting it were really worried about a lot of things. Their attitude rubbed off on me and I got more and more worried.\u003c/p>\n\u003cp>\u003cstrong>The donor’s samples — why didn’t you have those tested for things that could be dangerous?\u003c/strong>\u003c/p>\n\u003cp>I really thought about that. A part of it might have been foolhardy, but part of me was like the whole purpose of this experiment was to create an idea of how somebody could do something like this. A lot of people don’t have access to getting donors tested.\u003c/p>\n\u003cp>I thought the process I went through was pretty stringent. If you go to \u003ca href=\"http://www.openbiome.org/\" target=\"_blank\" rel=\"noopener noreferrer\">OpenBiome\u003c/a>, the website that takes fecal transplants from people and they freeze them to give to people, they have a questionnaire you can fill out to see if you qualify as a donor. It’s pretty extensive and it’s something I mimicked.\u003c/p>\n\u003cp>The major things that you’re probably worried about are more blood-borne diseases and illnesses. People always say you should be afraid of feces because of hemorrhagic E. coli. Honestly, I don’t think there is anybody who has hemorrhagic E. coli colonizing them and doesn’t know about it. So I wasn’t too concerned about that.\u003c/p>\n\u003cp>Maybe this sounds crazy, but there is a certain amount of trust that you want to be able to place in humanity or other people.\u003c/p>\n\u003cp>\u003cstrong>The donor was also your \u003cem>friend\u003c/em>. \u003c/strong>\u003c/p>\n\u003cp>Totally. It was kind of symbolic in that way. If I can’t trust this person, then we’re all screwed.\u003c/p>\n\u003cp>\u003cstrong>You said you want this kind of experiment to be accessible to people. Is that because you want people to be able to understand it easily, or do you see this as a prototype?\u003c/strong>\u003c/p>\n\u003cp>Kind of a prototype, but you have to understand, I don’t recommend this to people.\u003c/p>\n\u003cp>The position I’m in right now is really strange where I’ve become this “biohacker” figure. I get contacted by a ton of people all the time, and a lot of those are people with medical issues. And they have no treatment, no cure, and they’re just looking for help. They’re looking for some way they can treat themselves.\u003c/p>\n\u003cp>The U.S. unfortunately has decided to not allow doctors to prescribe feces to people for any disease other than Clostridium difficile infections that haven’t been able to be treated with antibiotics.\u003c/p>\n\u003cp>To me, that’s kind of disturbing. And the fact that people have the opportunity to seek treatment themselves, I think, is empowering. So what I really wanted to do was say, “Hey look, I tried to do something in a very scientific way. And I’m not saying it works, I’m not saying it’ll work for you or your disease or cure your ailments at all. But maybe you can also try to take your health into your own hands. Maybe if there’s no hope from the medical community, no hope for cures, you can perhaps figure out something on your own — through experimentation, through reading scientific papers — and help yourself.\u003c/p>\n\u003cp>\u003cstrong>The podcasters at \u003cem>The Verge \u003c/em>had some pretty harsh words for you. What did you think about that? \u003c/strong>\u003c/p>\n\u003cp>You know, I understand from a professional point of view what they were trying to do. But some of the stuff they said just cracked me up.\u003c/p>\n\u003cp>They said that what I was doing was stupid — which is hilarious when you’re talking about a person who is suffering from something. It’s like, “Hey, you’re suffering from some problem and I think you trying to help yourself is the stupidest thing you could do.”\u003c/p>\n\u003cp>They don’t know what it’s like when you have to go to the bathroom five times in an hour and\u003cb> \u003c/b>blood is spewing out of your butt and you’re in terrible pain.\u003c/p>\n\u003cp>People always bring up this issue about whether what I did was “scientific” or not. That critique is very dogmatic about the way that science is or should be done. What’s important about what I did was whether it works or not, right? I mean, if this actually worked, why wouldn’t people be interested? And look, I’m not trying to publish any of this, I’m not trying to have it peer-reviewed in any normal terms.\u003c/p>\n\u003cp>\u003cstrong>But you would like it if people took a look at what you did and said, ‘Maybe there’s something here.’\u003c/strong>\u003c/p>\n\u003cp>Yeah, but I think they know there is. There are clinics oversees, in the UK and other places that actually will give fecal transplants to people suffering from gastrointestinal illness. It’s something interesting that in the U.S. isn’t allowed.\u003c/p>\n\u003chr>\n\u003cp>We reached out to a handful of microbiome researchers for their thoughts on Zayner’s experiment. One, Owen White from the University of Maryland School of Medicine, responded.\u003c/p>\n\u003cp>“If I had a molecular biology background and was suffering from problems like Josiah, I would find it irresistible not to want to at least try some type of intervention on myself,” wrote White in an email.\u003c/p>\n\u003cp>“(T)here is something inherently deserving about exerting your own agency over things that you cannot ordinarily control,” White said. “That being said, I strongly agree with all the criticisms that were shown in the video.”\u003c/p>\n\u003cp>\u003c/p>\u003c/div>",
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"content": "\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003cem>For more, see Josiah Zayner’s \u003ca href=\"http://www.ifyoudontknownowyaknow.com/2016/05/i-transplanted-someone-elses-microbiome.html\" target=\"_blank\" rel=\"noopener noreferrer\">blog post about the transplant\u003c/a>, his \u003ca href=\"https://www.reddit.com/r/IAmA/comments/4i5euw/im_dr_josiah_zayner_former_scientist_at_nasa/\" target=\"_blank\" rel=\"noopener noreferrer\">AmA (Ask me Anything) entry on Reddit\u003c/a> or Arielle Duhaime-Ross’s \u003ca href=\"https://www.theverge.com/2016/5/4/11581994/fmt-fecal-matter-transplant-josiah-zayner-microbiome-ibs-c-diff\" target=\"_blank\" rel=\"noopener noreferrer\">coverage for The Verge\u003c/a>.\u003c/em>\u003c/p>\n\n\u003c/div>\u003c/p>",
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"tagline": "The flip side of gentrification, told through one town",
"info": "Gentrification is changing cities across America, forcing people from neighborhoods they have long called home. Call them the displaced. Now those priced out of the Bay Area are looking for a better life in an unlikely place. American Suburb follows this migration to one California town along the Delta, 45 miles from San Francisco. But is this once sleepy suburb ready for them?",
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"tagline": "Exploring the Bay Area, one question at a time",
"info": "KQED’s new podcast, Bay Curious, gets to the bottom of the mysteries — both profound and peculiar — that give the Bay Area its unique identity. And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.",
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"info": "KQED’s statewide radio news program providing daily coverage of issues, trends and public policy decisions.",
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"order": 8
},
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},
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},
"link": "https://www.cityarts.net",
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"order": 1
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"info": "\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />",
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"id": "commonwealth-club",
"title": "Commonwealth Club of California Podcast",
"info": "The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. This podcast feed is usually updated twice a week and is always un-edited.",
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"imageSrc": "https://cdn.kqed.org/wp-content/uploads/2024/04/Commonwealth-Club-Podcast-Tile-360x360-1.jpg",
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"source": "Commonwealth Club of California"
},
"link": "/radio/program/commonwealth-club",
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},
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"info": "KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.",
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"imageSrc": "https://cdn.kqed.org/wp-content/uploads/2024/04/Forum-Podcast-Tile-703x703-1.jpg",
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"source": "kqed",
"order": 9
},
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"meta": {
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},
"link": "/radio/program/freakonomics-radio",
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"id": "fresh-air",
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},
"hidden-brain": {
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"airtime": "SUN 7pm-8pm",
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"source": "NPR"
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"link": "/radio/program/hidden-brain",
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"how-i-built-this": {
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"title": "How I Built This with Guy Raz",
"info": "Guy Raz dives into the stories behind some of the world's best known companies. How I Built This weaves a narrative journey about innovators, entrepreneurs and idealists—and the movements they built.",
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"airtime": "SUN 7:30pm-8pm",
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"link": "/radio/program/how-i-built-this",
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"hyphenacion": {
"id": "hyphenacion",
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"tagline": "Where conversation and cultura meet",
"info": "What kind of no sabo word is Hyphenación? For us, it’s about living within a hyphenation. Like being a third-gen Mexican-American from the Texas border now living that Bay Area Chicano life. Like Xorje! Each week we bring together a couple of hyphenated Latinos to talk all about personal life choices: family, careers, relationships, belonging … everything is on the table. ",
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},
"jerrybrown": {
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"title": "The Political Mind of Jerry Brown",
"tagline": "Lessons from a lifetime in politics",
"info": "The Political Mind of Jerry Brown brings listeners the wisdom of the former Governor, Mayor, and presidential candidate. Scott Shafer interviewed Brown for more than 40 hours, covering the former governor's life and half-century in the political game – and Brown has some lessons he'd like to share. ",
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"order": 18
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},
"latino-usa": {
"id": "latino-usa",
"title": "Latino USA",
"airtime": "MON 1am-2am, SUN 6pm-7pm",
"info": "Latino USA, the radio journal of news and culture, is the only national, English-language radio program produced from a Latino perspective.",
"imageSrc": "https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/latinoUsa.jpg",
"officialWebsiteLink": "http://latinousa.org/",
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},
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},
"marketplace": {
"id": "marketplace",
"title": "Marketplace",
"info": "Our flagship program, helmed by Kai Ryssdal, examines what the day in money delivered, through stories, conversations, newsworthy numbers and more. Updated Monday through Friday at about 3:30 p.m. PT.",
"airtime": "MON-FRI 4pm-4:30pm, MON-WED 6:30pm-7pm",
"imageSrc": "https://cdn.kqed.org/wp-content/uploads/2024/04/Marketplace-Podcast-Tile-360x360-1.jpg",
"officialWebsiteLink": "https://www.marketplace.org/",
"meta": {
"site": "news",
"source": "American Public Media"
},
"link": "/radio/program/marketplace",
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"rss": "https://feeds.publicradio.org/public_feeds/marketplace-pm/rss/rss"
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},
"masters-of-scale": {
"id": "masters-of-scale",
"title": "Masters of Scale",
"info": "Masters of Scale is an original podcast in which LinkedIn co-founder and Greylock Partner Reid Hoffman sets out to describe and prove theories that explain how great entrepreneurs take their companies from zero to a gazillion in ingenious fashion.",
"airtime": "Every other Wednesday June 12 through October 16 at 8pm (repeats Thursdays at 2am)",
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"officialWebsiteLink": "https://mastersofscale.com/",
"meta": {
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"source": "WaitWhat"
},
"link": "/radio/program/masters-of-scale",
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"rss": "https://rss.art19.com/masters-of-scale"
}
},
"mindshift": {
"id": "mindshift",
"title": "MindShift",
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"info": "The MindShift podcast explores the innovations in education that are shaping how kids learn. Hosts Ki Sung and Katrina Schwartz introduce listeners to educators, researchers, parents and students who are developing effective ways to improve how kids learn. We cover topics like how fed-up administrators are developing surprising tactics to deal with classroom disruptions; how listening to podcasts are helping kids develop reading skills; the consequences of overparenting; and why interdisciplinary learning can engage students on all ends of the traditional achievement spectrum. This podcast is part of the MindShift education site, a division of KQED News. KQED is an NPR/PBS member station based in San Francisco. You can also visit the MindShift website for episodes and supplemental blog posts or tweet us \u003ca href=\"https://twitter.com/MindShiftKQED\">@MindShiftKQED\u003c/a> or visit us at \u003ca href=\"/mindshift\">MindShift.KQED.org\u003c/a>",
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