The stars of The Big Bang Theory are two fictional Caltech physicists, but the physics problems they study are real. Bill Prady, the program's co-creator and executive producer, talks about including real-world science in the script, from dark matter to magnetic monopoles.

Dengue fever, malaria and other tropical diseases took center stage at the American Society of Tropical Medicine and Hygiene conference. Nathan Seppa of Science News offers details, including a strange story of palm trees, fruit bats and human infection.

With NASA reporting a "significant amount" of water on the lunar surface, is it time to re-examine our priorities regarding living and working in space? Mark Sykes, director of the Planetary Science Institute, talks about why and how people should venture beyond Earth.

Researchers are hoping to improve solar energy installations by coupling a solar panel to an efficient hydrolysis unit that splits water into oxygen and hydrogen. Daniel Nocera of MIT says the approach could lead to personal solar power units that could get many houses off the grid.

The holiday season is here and for many that can mean a surge in stress. But what is stress exactly? Science Friday hit the streets of New York City to gauge stress levels and consulted with experts on the effects of stress and strategies for how to cope.