Scientists gather samples on the ocean floor.
Credit: Roger Linington.There's nothing new about looking to nature to cure disease – we've been doing it for thousands of years, with good results. (Two recent examples: The active ingredient in aspirin was first identified in the bark of the willow tree. And we have the Pacific yew tree to thank for one of the strongest anti-cancer drugs out there, Taxol.)

What's different about the work being done at the UC Santa Cruz Chemical Screening Center is that it a) looks to a largely unexplored medical resource: the ocean, and b) uses robots, rather than "forlorn-looking grad students" (to quote Center director Scott Lokey) to run the tests.

Here's a video I shot of one of those robots in action, with Lokey narrating.

One thing that didn't make it into the piece is that these researchers — including Lokey and Roger Linington — aren't just studying every disease they can think of. They focus on the diseases that commercial drug companies tend to neglect because there's so little profit in treating them – things like African sleeping sickness and cholera. So far, they're seeing progress on both, as well as breast cancer.

Listen to the Medicine from the Ocean Floor radio report online and check out images from this story in an online slideshow.

I was a biologist once, before I got into television, so I find these times particularly trying when I see schoolteachers and otherwise intelligent people calling evolution into question. That's part of the reason that I jumped at the chance to co-produce a story about bio-inspiration (the other reason being that I LOVE geckos…which will make more sense if you watch our QUEST Bio-inspiration segment).

Bio-inspired design borrows its creative inspiration from models and systems in nature, that is, plant and animal parts that have been slowly tweaked for over 3.8 billion years. But that doesn't mean that nature's designs are perfect. In fact, that's what makes the process of engineering things based on natural models so difficult. You have to figure out how to pull the aces from the evolutionary discard pile. As professor Bob Full at U.C. Berkeley explained in our first phone conversation, that's also why scientists now use the term "bio-inspiration" rather than the more commonly known term "biomimicry." Biologists and engineers are not looking to simply mimic nature, because there are all kinds of dead ends and redundancies in natural systems that would be pointless to recreate in an optimized, man-made piece of technology. One of the examples he gave me is a kind of grasshopper that if you were to copy it, you would copy neurons that go to nothing, they don't connect to any muscles, and that's because during evolution the adults lost their ability to fly. The neurons going to the muscles are still there, but the muscles aren't there anymore. No need to copy that, right?

So what a biomimeticist does is look to nature to find plants & animals with remarkable performance abilities, and studies their adaptations for inspiration to design something new. For example, if you want to make a tiny robot that can fly, then look at the best fliers. If you want to design a blade that moves quickly through fluids, or an Olympic swimsuit that minimizes drag, then look to the most efficient swimmers. Now that's what I call "intelligent design!"

Watch the Bio-Inspiration: Nature as Muse television story report online.

The term "artificial intelligence", was coined in the summer of 1956, on the bucolic grounds of Dartmouth College in Hanover, New Hampshire. There, John McCarthy (who would later go on to teach at Stanford), Marvin Minsky, Claude Shannon, Nathan Rochester and six other conference participants came together to lay out the framework for this exciting new field which would "…find how to make machines use language, form abstractions and concepts, solve kinds of problems now reserved for humans, and improve themselves." (McCarthy et al., 1955)

Though it was McCarthy who persuaded his nine other colleagues at the conference to adopt the term "artificial intelligence" to describe the nascent field, the seeds of artificial intelligence were planted earlier. Alan Turing, who was instrumental in breaking the German's Enigma code during WWII, published a paper in 1950 that laid out what came to be known as the "Turing Test:" if a machine could carry out a conversation with a human in such a sophisticated manner as to trick the human into thinking that he or she was conversing with another human, then the machine would have displayed true "intelligence."

But nearly 60 years later, the world still awaits a machine capable of exhibiting "general A.I.", instead of the "narrow A.I." demonstrated by IBM's chess-playing Deep Blue or Stanford University's Stanley, an autonomous robotic vehicle, or other impressive albeit limited applications of A.I. For example, Deep Blue may be able to beat Gary Kasparov at chess but can it beat a 10 year-old at a game of checkers? The lack of a general A.I. is made even more stark when juxtaposed with Moore's Law, a maxim that goes back to 1965 when Intel founder Gordon Moore postulated that the number of transistors on a computer chip would double roughly every 18 months.

There's even a term – "Singularity" – that is being used to describe the moment when technological progress will leapfrog and herald the creation of computers that not only achieve human-like intelligence, but also give rise to a progeny of computers who will be smarter then their digital forbears. Though he didn't coin the term (sci-fi writer Vernor Vinge did), the most famous exponent of this belief is inventor Ray Kurzweil. He places the Singularity as occurring sometime before 2050 and believes that with the advent of this unheralded technological progress, mankind may solve some of our society's most pressing ills, such as global warming, and even conquer death, by uploading one's consciousness into a virtual medium.

Though this seems a far stretch from engineering a domestic robot like Stanford's Artificial Intelligence Robot, top A.I. researchers like Stanford's Andrew Ng and Daphne Koller do believe that computing systems will some day be as smart or smarter than humans. When I spoke with Dharmendra Modha about his work into cognitive computing at IBM, he talked effusively about creating an "i-Brain," a digital accessory that people could carry around, making decisions and processing information like its human cousin. But if you're like me, and lament those moments when you've misplaced your keys or other instances of poor neural performance, you can't help but think that such a device can't arrive soon enough. On second thought, I'll wait until v2.0 hits the shelves.

Watch the Artificial Intelligence: Thinking Big television story report online.

And don't miss our Web Extra: A Dose of A.I. In this QUEST web exclusive, Stanford University computer science professor and artificial intelligence (A.I.) researcher Daphne Koller provides an elegant explanation of how A.I. can be employed in the examining room to diagnose a patient's illness more accurately than a human clinician. Find out more and learn how medical diagnosis is just the tip of the iceberg when it comes to tasks that rely on making sense of a sea of data to arrive at an informed conclusion.

Forward camera view from Opportunity as the rover attempts to
climb up a slope toward the wall of Victoria Crater.
Photo by NASA/MER/Opportunity.Is there life on Mars? Well, that investigation is still ongoing–but from a cybernetic perspective, the surface of Mars is literally crawling with it: in the form of robots!

Four years after their planned three-month tour of duty began, NASA’s Mars Exploration Rovers (MER) Spirit and Opportunity roll doggedly on like a pair of aged, dusty desert prospectors looking for gold. In this case the "gold" is evidence for past water on Mars, and signs of that seem to abound.

What sparked this blog for me was the announcement of the plan to send Opportunity out of the depths of Victoria Crater, the half-mile impact crater that the rover has been exploring for almost a year now. Last September, when it was decided to send Opportunity into Victoria to get a close-up view of the sedimentary rock layers exposed in the crater walls, there was a lot of talk about this expedition possibly being the rover's last–it almost sounded like the robot was being sent into its own grave, its final resting place on Mars. After all, the rover had already operated ten times longer than what it was designed for!

What did Opportunity's year-long sojourn yield? By examining the multitude of exposed sedimentary layers, it is believed that those layers were probably originally laid down by wind (not a surprise on Mars, which even today is a world of wind-blown dust: dust devils, sand dunes, planet-wide dust storms). But there are also clues written in the rocks that the layers of sediment have been modified by the action of water.

One particular thing Opportunity has discovered are rock features dubbed "fins." These fins are raised edges around rock boundaries that are rich in the mineral hematite–a mineral that often forms in the presence of water. Opportunity found hematite on Mars early in its exploration, which supports the speculation that at least that rover’s region on Mars (Meridiani Planum) may have harbored at least shallow and intermittent bodies of water in the past.

The "fins" may have been formed when water dissolved away areas of sediment and then "filled in the holes" with deposited minerals–forming a kind of "fossil" of what was once an empty space.

When I lived in Northern Arizona, I remember driving across the plains east of Flagstaff and finding long, wide ridges of what looked like sandstone, snaking across the dusty desert like enormous gopher trails. I learned that these were the fossil remnants of what were stream beds: the streams formed deposits of sand and mud in their bed, which over time hardened into sandstone and mudstone. Later, the softer surrounding soils and sands eroded away, leaving the hardened stream beds as raised ridges of rock–dry evidence in a dry desert of past liquid water action. Though this is not the same process that formed the fins on Mars, it is analogous.

But now Opportunity's mission in Victoria Crater is done, and NASA is making plans to have the robot crawl back up the slope and exit the crater at the same place it entered last September. It will continue its mission by examining "cobbles"–small, loose stones on the surrounding planes, some of which were probably ejected by meteorite impacts in Mars' distant past.

Spirit, on the other side of the planet in Gusev Crater, is also still alive, and is making ready to do a bit more roving after a Martian winter of relative inactivity. With one of its six wheels no longer functioning, Spirit will limp along and continue prospecting–next stop: some white, silica-rich material that may have formed in hot water.

NASA's MESSENGER spacecraft at Mercury-artist concept.

Photo by: NASA

I've been waiting for the "whole story" on Martian ice at the Phoenix lander site to unfold more completely, but the chemical analyses have not yet run their full courses-so I've decided to widen the focus on this blog to give a status report on current active robotic exploration of planets going on around the Solar System.

Limiting my scope to only planetary spacecraft, the list is still respectable. In no particular order, here's the round-up:

Spirit: Mars Exploration Rover Spirit's activities on the Martian surface have been reduced to save on power, but the robot remains alive. With the arrival of Martian winter, Spirit spends more power running heaters to keep key electronic and power equipment healthy. Spirit remains in the giant Gusev Crater, where it will spend its entire life on Mars.

Opportunity: Exploring a much smaller crater of its own, Victoria Crater-Spirit's twin, Opportunity, continues its investigation of the rock layers of Mars' geological history. As of June 10, Opportunity has clocked in at 7.26 miles of total "roving" on Mars, since its landing back in 2004.

Phoenix: The brand-spankin'-new Mars Phoenix lander has been digging into one of Mars' greatest scientific mysteries: water. Detailed chemical analysis of samples taken at Phoenix's site near the northern polar ice cap is underway, but the big question– is Phoenix standing on frozen Martian water– has been answered: yes.

Mars Reconnaissance Orbiter: The newest orbiter in the Martian fleet continues to send back its extreme-high-resolution imagery and its revealing chemical measurements, as well as to serve as a high-speed data and communication relay for other Mars-exploring robots.

Mars 2001 Odyssey: Credited with detecting the massive amounts of frozen water in Mars' northern hemisphere-the same ice that the Phoenix lander is now scraping at, Mars 2001 Odyssey continues its surveillance of Mars' chemistry and atmosphere.

Mars Express: The European orbiter that launched the ill-fated Beagle II lander has continued on a respectable career of exploration in its own right. Mars Express also helped support the landing of the Phoenix.

Cassini: Saturn's first robot-in-residence, Cassini, has concluded its initial 4-year mission and is now continuing on an extended mission. Cassini has given us unprecedented close-up images and measurements of many of Saturn's stunning moons, its complicated ring system, and the swirling, aurora-touched cloud formations of Saturn itself.

MESSENGER: The first spacecraft to visit the little-understood Mercury since 1975 made its first flyby of that planet last January, and will settle into a permanent orbit in March 2011. Even the few pics it snapped as it hurled by gave us far more detailed images of Mercury than ever before.

New Horizons: Launched a couple years ago on its outward bound, meteoric flight to Pluto, New Horizons has already performed some exploration duty, capturing images and data of Jupiter, Jupiter's volcanic moon Io, and Jupiter's long magnetic "tail." Now in "cruise mode," this little robot will fly past Pluto (dwarf planet; king of the Plutoids) in July 2015.

Voyagers 1 and 2: Do you remember the remarkable voyages of discovery made by the Voyager spacecraft, both launched in 1977? Since completing their primary missions of flying by the Gas Giant planets (Voyager 1 at Jupiter and Saturn, Voyager 2 at all four), these two veterans have continued to operate and send information back to Earth, and are now about 3 times more distant from the Sun than Pluto.

That's the wrap. If I missed anyone, my apologies!

The DARPA Grand Challenge is one of the most unusual car races in the world. In this race, the cars drive themselves – no remote controls needed. And the contest is not a game. It could change the way all of us drive. We visited the leading Bay Area team, the Stanford Racing Team, as they geared up for this year’s race.

The race is sponsored by the Department of Defense's research division, known as DARPA. Their goal is to convert one-third of their ground vehicles to unmanned vehicles. That's where the contest comes in– to develop the technology needed for such an application. Early uses could be surveillance on the ground or convoy missions, but they haven't ruled anything out. What are your thoughts on the wartime purpose of this contest?

The Stanford team, like many others, see this technology being used far and wide in the future. The laser sensors that the robots use are much more accurate than human eyes. So, robotic cars could follow each other very closely, which could have major impacts on traffic and the need for new roads. Autonomous vehicles could help elderly and disabled drivers, too. It sounds like science fiction, but scientists are on their way. Would you use a robotic car?

UPDATE: The Stanford Team's car, Junior, took second place in the race this past weekend. I've heard it was a very close race with six team completing the whole course. Check out the full race results or read a San Francisco Chronicle article on the finals.

You may listen to the "Robot Car Race" Radio report online, as well as find more resources. Also, don't miss our behind-the-scenes photos for this story on flickr.com.

Lauren Sommer reports for QUEST and Radio News at KQED-FM.

latitude: 37.4265, longitude: -122.077