Every Thursday, the California Academy of Sciences is transformed into a lively venue filled with music, provocative science, mingling, and cocktails for visitors 21 and older. Activities and performers change week to week. Image courtesy Jenny Oh.

Over lunch today, I got into a debate with my friend over which camp I fell into – nerd or geek. His understanding is I lacked the technical aptitude to fall into either category. Of course, I disagreed. I am quite confident that I am situated comfortably in the nerd camp. His rebuttal was that I throw parties for a living of which I countered that I throw “science” parties.

So at an impasse, definitions were in order – both are quoted form the Merriam-Webster Dictionary:

Nerd
Function: noun
Etymology: perhaps from nerd, a creature in the children's book If I Ran the Zoo (1950) by Dr. Seuss (Theodor Geisel)
An unstylish, unattractive, or socially inept person; especially one slavishly devoted to intellectual or academic pursuits

Geek
Function: noun
Etymology: probably from English dial. geek, geck fool, from Low German geck, from Middle Low German
1: a carnival performer often billed as a wild man whose act usually includes biting the head off a live chicken or snake
2: a person often of an intellectual bent who is disliked
3: an enthusiast or expert especially in a technological field or activity

“Slavishly devoted to intellectual or academic pursuits” definitely rings a bell. I love researching and I always have. In high school, the librarians knew me by name because I spent more time with books than peers. In college, I would pick paper topics specifically to gain access to the Bancroft rare books library at Cal. In school, it was easy to fuel my nerdy interests and get lost into a battle of wits amongst friends but in adulthood, I have had to search for like-minded people and events. Below is my list of favorites intellectual haunts in the city.

NightLife at California Academy of Sciences

Okay, I am totally biased as I manage the music and programming for the series. But I don’t think I would have explored so many other events if I wasn’t working on creating a “science” party of my own.

Down to a Science Informal Lectures at Atlas Café

This past Monday, I heard Brian Fisher talk about ants at this series. His stories, passion, and enthusiasm filled the room and the audience was captivated. Not only did we see into the fascinating world of ants but we found out why Dr. Fisher screens his calls. His number one question from the public is ‘How do I get rid of the ants in my kitchen?’

Down to a Science Book Club at Book Inc.

In January, we are reading Dr. Tatiana’s Sex Advice for all Creation which is one of my all-time favorite science books. In the past month, I was introduced to the amazing medical mystery of Prions. The discussion has been small and incredibly lively each time I’ve attended.

Exploratorium after Dark

Okay, I have to admit that I haven’t been to this particular event yet because I work on NightLife on Thursday nights. But I have a group assembled to go check it out during our hiatus in December. I love that they are doing a night like this as I HEART the Exploratorium. I have ever since I visited during bubble day and was able to step into a giant bubble thanks to a lot of bubble solution and a simple pulley system.

LoveTech usually held at Il Pirata

I attended LearnTech which is a part of this series to support my friend who built a navigation portal into fractals. This is a great event that plays with the intersection between art, electronics and music. LearnTech was set up as mini talks and tabling. The talks, interaction, and boundless creativity had me captivated.

Ask a Scientist Informal Lectures held at Axis Café

This is another informal Science Café that has great content. The last one I was able to attend delved into the science behind magic. Even thought the place was packed, the lecture and discussion were lively and funny to boot.

Bookswap held at Booksmith

Reading, being my portal into nerdiness, is a constant pastime. But there are very few times that I get to truly discuss a book let alone several. I brought Mary Roach’s Bonk and swapped it for a Ninja novel. I was also given the recommendation of World War Z. I read it in two days; itt was so well written and absolutely engrossing.

What’s wonderful about San Francisco is this is only a slice of science events in the city. Have you found a haunt in the San Francisco Science Scene? Feel free to share you’re favorites in the comment section below.

H1N1 flu

The vulnerability translated to substantial number of deaths, estimated to be between 2,500 and 6,100 according to the CDC. There is good news on the horizon, as week to week indicators show both a decline in national doctor visits for the flu and there has been a substantial decline n number of states reporting widespread H1N1 activity.

This may be sign of the H1N1 outbreak peak, a figure Art Reingold has been closely monitoring for the past few months. He'll be discussing the epidemiology of the pandemic and the controversy over the vaccine.

To learn more about the H1N1 virus, call: (800) CDC-INFO (800 232-4636) or visit the CDC's website.

H1N1 Update with Dr. Art Reingold
When: Wednesday, December 9th, 7-9 PM
Where: Cafe Valparaiso at La Pena Cultural Center
Cost: Free
Details: Experts are predicting a substantial resurgence of swine flu cases this coming winter. Art Reingold will provide an update concerning the global pandemic of novel H1N1(swine) influenza; the current state of affairs in the US and California; and options for prevention, including a pandemic influenza vaccine.

Geek Out by taking the Mars Survival Challenge

Forget the challenging landscapes of the Arctic or Everest; if you want a true survival test, how about Mars? Our red neighbor has inspired thousands of intrepid explorers (and a number of awful movies) to formulate colonization plans. With a little help from Google Mars, you can choose plot near all the important landmarks: Valles Marineris, Olympus Mons, or even the famous northern polar ice caps.

Thanks to our friends at the Lawrence Hall of Science, you too can help the colonization effort. At their Geek Out event on 11/18, you’ll be able to design your own Mars Base. There will be experts on hand from the SETI Institute and NASA to provide some info on the Martian landscape and what it takes to survive there.

You’ll be able to videotape your landscape to share with the rest of the universe. Who knows, the first ever Martian colony could be named after you!

This is the 2^nd LHS Geek Out event, a new monthly science series for adults. The evening will be full of interactive science, music, and cocktails. There is also a free shuttle from the Downtown Berkeley BART to the museum. For a primer, check out this video from the 1^st Geek Out event.

LHS Geek Out: Mars Survival Challenge
When: Wednesday 11/18, 7-10 PM
Where: Lawrence Hall of Science, Berkeley
Cost: $10, $8 for members and UC Berkeley Students
Details: Come to Lawrence Hall of Science, grab a drink and a friend, and get ready for some downright nerdy fun. All events include full access to exhibits, a cash bar, hors d’oeuvres, and of course the best view in the East Bay. Program is for adults only.

The Exploratorium turns 40!

The Exploratorium opened quietly that fall, slowly changing the way science museums are organized and oriented to their audiences. It combined a living laboratory, art, and interaction under one roof; the result is a place where science is accessible and owned by all.

In celebration of this anniversary, the Exploratorium is hosting a number of events at the museum over this weekend. Plus they are throwing in quite a treat…admission is free all weekend (November 7-8). For a full list of activities and an exceptional history of the museum, check out the Exploratorium’s 40^th anniversary website.

Exploratorium After Dark: Electrifying Science with Dr. MegaVolt
When: Thursday 11/5, 6-10 PM
Cost: Free for members, $14 for non-members (Adults 21+ only)
Details: Blow your mind with the electrifying science of Tesla coils and Austin Richards, PhD—aka Dr. MegaVolt. This electrifying Exploratorium Science After Dark will feature Dr. MegaVolt jousting with 14-foot electrical arcs from his high voltage Tesla Coil.

Cutting Ice into One with a Motorcycle
When: Saturday 11/7
Cost: Free
Details: Imagine a big block of ice suspended from the ceiling of the Exploratorium. Now imagine a wire wrapped around the middle of that ice block from which is hung a motorcycle. Chill out with other skeptics and watch the motorcycle fall to the floor as the wire very slowly cuts through the ice, but bear witness—the ice block remains one whole piece!

Iron Science Teacher
When: Sunday 11/8, 2-3 PM
Cost: Free
Details: Cheer on the competitors in this zany science cook-off, where teachers compete before a live audience for the revered title, 'Iron Science Teacher.' In recognition of the Exploratorium’s 40th birthday, this special edition of our popular show features a secret ingredient closely related to birthdays!

Something Incredibly Wonderful Happens: Frank Oppenheimer and the World He Made Up – A Conversation with Author K.C. Cole
When: Sunday, 11/15 at 3 p.m
Cost: Free with admission to the museum
Details: Discover the never-before-told story of Frank Oppenheimer, physicist, educator, brother of J. Robert Oppenheimer, and founder of the Exploratorium. Believing that “without understanding, we’d all be sunk,” Frank Oppenheimer created the Exploratorium to be a museum of human awareness that combined art and science while encouraging play, experimentation, and a sense of joy and wonder.

The Bay Area Festival of Science

Every year, Wonderfest pairs researchers to answer provocative questions in the world of science. The point is to create an engaging dialogue between the scientists and the audience, empowering people to make up their own mind.

I’m always blown away by the scientific luminaries that take part in the dialogues. Just last year, there was a dialogue on our energy future featuring current Secretary of Energy (and Nobel Laureate) Steven Chu and co-lead author of the IPCC report on climate change Dan Kammen.

This year is no exception with an expanded line-up of exceptional dialogues:

Does Moore’s Law Apply to Energy Technology?
Does Media Violence Inspire Real Violence?
Is Evolution Still Darwinian?
Do Robots Make Better Astronauts?
Does Darwin Illuminate Emotion & Spirituality?
Can We Create Life?

Dialogues not your thing? This year brings the debut of the Amateur Science Forum, (exhibitions of local citizen science programs), the Bay Area Science Expo (shop for science inspired books, crafts, and music), and my personal favorite: the Mind Duel. The Mind Duel is a science quiz competition between a local high champion and a panel of local science professors. A Nobel Laureate humbled by a local high student…it’s possible and likely at Wonderfest.

Wonderfest 2009

When: Saturday 11/7 1-10 PM, Sunday 11/8 10 AM -5 PM
Where: Saturday – Hewlett Teaching Center, Stanford University
Sunday – Stanley Hall, UC Berkeley
Cost: FREE
Details: Through public discourse about provocative scientific questions, Wonderfest aspires to stimulate curiosity, promote careful reasoning, challenge unexamined beliefs, and encourage life-long learning. Wonderfest achieves these ends by presenting series of scientific events to the general public. At most of these events, pairs of articulate and accomplished researchers discuss and debate compelling questions at the edge of scientific understanding.

Prion diseases are neurodegenerative, attacking the brain. Could they be responsible for the recent wave of Zombie attacks across the globe? Original photo: digitalsextant.

But what if there existed a substance that acted like a virus or bacteria but wasn’t living? Medicine made a revolutionary leap during the time of Louis Pasteur in the mid 1800's. The inventor of food pasteurization and one of the founding fathers of microbiology – he was able to prove germ theory. Food spoiled and organisms got sick because of the growth of bacteria and viruses within them. Within sterile environments, viruses and bacteria could be killed off and food could be preserved or organisms could recover from illness or infection. Sterilization works on living micro-organisms. Prions, however, are not living organisms.

Prions are infectious proteins. For unknown reasons, these proteins refold abnormally and cause a domino effect in surrounding proteins which in turn mutate into stable structures. Prions will then cause tissue damage and cell death to surrounding areas. Prion diseases are neurodegenerative, attacking the brain and are characterized by "holes" in the tissue. The incubation time for Prion diseases is quite long. They usually surface later in life but after they surface, the diseases are rapid and fatal. Such examples of Prion diseases include Mad Cow Disease in cattle, Scrapie in sheep and Fatal Familial Insomnia in humans. FFI is a disease that literally takes away the ability to sleep and in a few months leads to death. The Book “The Family That Couldn’t Sleep” by journalist D.T. Max follows a family in Italy that passes this disease from one generation to the next over subsequent centuries.

Prions have been and still are a medical mystery. What causes them to mutate and aggressively eat away at the brain? How can they be stopped? Because they are not living they are highly resistant to sterilization methods. While viruses and bacteria can be eradicated on equipment through heat, radiation or chemical reagents, Prions are strongly immune. Maybe Zombies are not so far off after all – lurking in the shadow of medicine has been a mutation that is resistant, brain-eating and neither alive or dead. It has some serious similarities to the zombies I have watched over and over again on the big screen.

If you want to learn more about Prions and their history, check out Down to a Science’s next reading group which is focusing on the book The Family that Couldn’t Sleep or check out the book Deadly Feasts: The "Prion" Controversy and the Public's Health by Richard Rhodes. And one more thing – Happy Halloween!

The Sloan Telescope used to conduct BOSS

One of those is BOSS, the Baryon Oscillation Spectroscopic Survey, is a new project to create a 3-D map of over 2 million galaxies and quasars representing the best data ever obtained on the large-scale structure of the universe. Baryon oscillations began as pressure waves through the hot plasma of the early universe. Those waves left an imprint on the matter that makes up the universe, including the dark matter. The survey will essentially act as a ruler, in order to measure how the universe has been expanding.

Next Monday, you’ll be able to meet David Schlegel, the principal investigator of BOSS. He’ll be part of a panel of Lawrence Berkeley Laboratory scientists discussing their search for dark energy. As a primer, check out QUEST’s story on Dark Energy from last year. The piece features astrophysicist Saul Perlmutter, who will also be speaking at the event.

See QUEST's Video on Dark Energy below:

QUEST on KQED Public Media.


Dark Secrets: What Science Tells Us About the Hidden Universe

Where: Berkeley Repertory Theater, 2025 Addison Street, Berkeley

When: Monday, October 26th 7-830 PM

Cost: FREE

Details: No mystery is bigger than dark energy — the elusive force that makes up three-quarters of the Universe and is causing it to expand at an accelerating rate. KTVU Channel 2 health and science editor John Fowler will moderate a panel of Lawrence Berkeley National Laboratory scientists who use phenomena such as exploding stars and gravitational lenses to explore the dark cosmos.

This year's Wildlife Conservation Network Expo in full swing at the Mission Bay Conference Center.

It’s a sunny, fall day in October and I am driving into San Francisco. I pass the colorful Love Parade floats revving up without a glance of longing. I pass the turn towards Golden Gate Park for Hardly Strictly Blue Grass Festival without an ounce of FOMO (fear of missing out). I giddily park outside of Mission Bay Conference Center and enter the Wildlife Conservation Network’s yearly Expo. Parades and music will have to wait; I am ready to gorge myself on colorful wildlife and rock star conservationists. Each year I am more amazed and enthralled by this extraordinary event.

The Wildlife Conservation Network (WCN) was founded in 2002 in Los Altos by Charlie Knowles and Akiko Yamazaki. Their unique approach to conservation is based on the venture-capitol model and offers organizations expert networks, fundraising support, global exposure and Silicon Valley expertise. 100% of donations to WCN go to programs. It is an efficient system with measurable results and an excellent example of conservation action.

The Wildlife Conservation Expo is a dream come true for wildlife people, and after many years of attending, it feels like an international family reunion of cousins related by their passion for animals and the natural world. Flying in from 30 countries, including the mountains of Uganda, the savannahs of Zimbabwe or the steppes of Uzbekistan, they come together to share their miraculous projects. I marvel that I simply need to navigate the s-curved bridge from Oakland to be amongst this kin of conservation heroes.

The day consists of short and sweet speaking sessions from these 24 wildlife powerhouses, each one more inspiring than the next. Between sessions, participants visit the many tables featuring local, national and international groups and projects. The Oakland Zoo table was surrounded by such favorite groups as Africa Matters, Animals Asia, WildAid, Reptile & Amphibian Ecology International, Project Tamarin, Mountain Gorilla One Health Program, Red Panda Network, Elephant Voices, or our Teen Wild Guide’s favorite, The Saiga Conservation Alliance. Add in mingling with hundreds of like-minded people, and it is a day that can’t be beat. Oh, did I mention Jane Goodall is the keynote speaker? As I write this, I watch her graciously speak with participants, sign books and scratch the head of one of the Working Dogs for Conservation. Lucky dog.

At Dr. Jane’s presentation, she begins with her uncanny chimp-like pant-hoot greeting and reminds us that passion is the most powerful asset one could have. That if we all explored and exercised our passions, what a different world it would be. As usual, I leave WCN with new ideas, new reasons to be hopeful and renewed gratitude for WCN.

The 2010 dates have yet to be decided. Watch the website for details.

David experimenting with EEG

David takes “guinea pig” journalism to super size me heights. He was tested by numerous genetic sequencing companies, had dozens of brain scans, gave gallons of blood for toxicity tests, even had a virtual colonoscopy to understand what “personalized” medicine means for him. His experimentation was divided into 4 categories: genetics, environment, brain, and body.

My favorite experiment was a memory test in which David and I both participated. The study was on how normal aging changes the neural mechanisms of memory and attention; a study run by Dr. Adam Gazzaley of UCSF. His lab uses a combination of techniques including fMRI (functional magnetic resonance imaging -measures blood flow using a big magnet), EEG (electroencephalography – measures electrical signals in the brain), and TMS (transcranial magnetic stimulation – using a magnet to “scramble” regions of the brain).

In this experiment, I was getting an EEG, designed to measure electrical signals of the brain, in this case studying regions controlling memory and attention. I was fitted with a stylish red cap, my head was covered with a conductive gel, and I was seated a few feet from a computer screen. After some careful measurements of my head, I was ready to go.

I was shown either a face or nature scene for a split second, then the screen went blank, then I was shown another face or nature scene. My task was to decide whether the two pictures were the same. Sounds exceedingly simple, but it was far from it. I left absolutely exhausted after just a few hours!

However, my results were excellent. I averaged about 95% correct over 3 hours. According to the researchers, that’s slightly better than the average 18-35 year old. David’s results were about the same, but he is more enthusiastic considering he’s closer to 50. Take a simpler version of a brain age test online.

The Experimental Man with David Ewing Duncan

Where: Atlas Cafe, 3049 20th St @ Alabama St.

When: Monday, October 19th 7-9 PM

Cost: FREE

Details: David Ewing Duncan discusses his new book “The Experimental Man”, his book exploring what cutting-edge technologies in personalized medicine can tell us about individual health and life — past, present and future: genes, environment, brain and body.

As the impact grows closer, NASA is making an effort to talk about the locally driven mission. Many of the upcoming talks are suitable for any audience, from kids to adults.

Luna Philosophie: Hitch-hiking to the Moon

Where: Scribd, 539 Bryant St. (2nd Floor), San Francisco

When: Wednesday, 9/23 6-8 PM

Cost: Free, RSVP to Delia.L.Santiago@nasa.gov

Details: Dr. Kim Ennico, LCROSS Payload Scientist and the LCROSS Payload Integration & Test Manager, will provide an overview of the NASA LCROSS mission and discuss how NASA has been expanding the concept of “participatory exploration” with LCROSS as an example. This will be a lively discussion.

Andrew Chaikin on LCROSS

Where: Chabot Space & Science Center

When: Saturday, 9/26 3-430 PM

Cost: Free with Museum Admission

Details: Author, speaker, and space journalist Andrew Chaikin joins Chabot visitors for a night of moon conversation and exploration. Using the detailed program Google Moon, which he helped to develop, Chaikin takes the visitor on a guided tour of the moon’s surface. Chaikin will also discuss the recent LCROSS mission and his extensive knowledge of the Apollo missions.

To the Moon: A Look at NASA’s Upcoming Lunar Impact Mission and the History of Moon Exploration

Where: Exploratorium

When: Sunday, 9/27 2-4 PM

Cost: Free with Museum Admission

Details: Take a trip to our nearest neighbor in space with renowned science journalist and space historian Andrew Chaikin. Relive the achievements of Apollo lunar astronauts and learn about the ambitious LCROSS mission, which will send a rocket crashing into the moon’s permanently shadowed regions to kick up huge plumes of debris in the hopes of uncovering deposits of ice. In addition, Exploratorium educators will give an entertaining and interactive overview of moon science.

QUEST on KQED Public Media.