Bio-inspired design borrows its creative inspiration from models and systems in nature, that is, plant and animal parts that have been slowly tweaked for over 3.8 billion years. But that doesn't mean that nature's designs are perfect. In fact, that's what makes the process of engineering things based on natural models so difficult. You have to figure out how to pull the aces from the evolutionary discard pile. As professor Bob Full at U.C. Berkeley explained in our first phone conversation, that's also why scientists now use the term "bio-inspiration" rather than the more commonly known term "biomimicry." Biologists and engineers are not looking to simply mimic nature, because there are all kinds of dead ends and redundancies in natural systems that would be pointless to recreate in an optimized, man-made piece of technology. One of the examples he gave me is a kind of grasshopper that if you were to copy it, you would copy neurons that go to nothing, they don't connect to any muscles, and that's because during evolution the adults lost their ability to fly. The neurons going to the muscles are still there, but the muscles aren't there anymore. No need to copy that, right?

So what a biomimeticist does is look to nature to find plants & animals with remarkable performance abilities, and studies their adaptations for inspiration to design something new. For example, if you want to make a tiny robot that can fly, then look at the best fliers. If you want to design a blade that moves quickly through fluids, or an Olympic swimsuit that minimizes drag, then look to the most efficient swimmers. Now that's what I call "intelligent design!"

Watch the Bio-Inspiration: Nature as Muse television story report online.

Human and chimpanzee chromosomes are very similar.
Note that human chromosome 2 is very similar to a
fusion of two chimpanzee chromosomes.

For the last few weeks I have been corresponding with someone about intelligent design (ID). More specifically, we have been chatting about why humans have 46 chromosomes and most of the great apes have 48.

To me, this is great evidence for evolution. Why? Because if you look at the chromosomes closely, you can see that human chromosome 2 is really just a fusion of two great ape chromosomes.

The idea is that a few million years ago, a common human-chimpanzee ancestor of ours had two of his or her chromosomes fused together. This sort of thing happens all the time even today. Around 1 in 1000 live births has one of these kinds of fusions.

Then, probably through chance,this ancestor with the fused chromosomes went on to found the human race. Now people have 46 chromosomes and chimpanzees have 48.

An alternative explanation is that the designers fused the two chromosomes together when they created humans. The idea would be that the designer wouldn't create every plant, animal, bacteria, and virus from scratch–why reinvent the wheel every time? Instead the designers would mix and match parts that worked.

So as part of the process of designing a human, the designer fused two ape chromosomes together. This would presumably be simpler than creating a human chromosome 2 the way the other chromosomes were made.

The difficulty with this idea is that there is no obvious advantage to having 46 chromosomes instead of 48. What matters is our DNA, not how it happens to be packaged.

It is possible that there was some advantage to fusing the chromosomes together. For example, maybe a new gene was created at the fusion point. Or maybe genes that were shut off before were now turned on in the new fused chromosomes.

There isn't any evidence of these kinds of things. And even if there were, a designer who can easily put in the 60 million or so differences between humans and chimpanzees should be able to accomplish whatever results a chromosome fusion gives more elegantly than sticking two ape chromosomes together.

Also, when you look at the fusion point, you can see that the DNA isn't exactly what you would expect if a fusion happened in the last 10,000 or even 100,000 years. The results look more like an event that happened millions of years ago.

The ends of a chromosome have a defined sequence of DNA repeats called a telomere. The DNA at the fusion point looks very similar to a string of telomeres (as we would expect from a fusion) but it isn't perfect. This is just what you would expect if the fusion happened millions of years ago. Because our DNA gets changed a little all of the time.

The environment or even our own cells can cause the wrong letter to end up in our DNA. Our cells are pretty good at fixing these mistakes but they don't catch them all. What this means is that our DNA builds up mutations over time.

When an unfixed change happens in a sperm or egg, then it is passed down to the next generation. If the changes that aren't fixed happen somewhere important, then they are selected for or against. But if they're neutral, then they just build up over time. Scientists can even use these sorts of errors to predict how long ago something happened. Or to trace human migration patterns.

These DNA changes at the fusion point do not fit with ID if they don't serve a purpose. Otherwise, why put them there? It will be interesting to see the results of experiments that might show if these sequences matter or not.

Dr. Barry Starr is a Geneticist-in-Residence at The Tech Museum of Innovation in San Jose, CA.